Publications by authors named "Ramakrishna Borra"
Mechanistic Insights into Tau Protein-Mediated Regulation of Oxidative Stress.
Zhongguo Ying Yong Sheng Li Xue Za Zhi
October 2024
Article Synopsis
- Abnormal tau protein behavior, including hyperphosphorylation and aggregation, is a major feature of tauopathies like Alzheimer's disease, leading to neurodegeneration.
- The interaction between oxidative stress and tau pathology is complex, with both factors contributing to neuronal damage through impaired microtubule stability and transport.
- Further research into oxidative stress sources, such as microglial cells, could improve our understanding of tauopathies and aid in developing new treatment strategies.