Publications by authors named "Ramachandra Yelamanchi"
Revisiting Friedreich's Ataxia: Phenotypic and Imaging Characteristics.
Ann Indian Acad Neurol
April 2024
Article Synopsis
- Friedreich's ataxia (FRDA) is an inherited condition leading to cerebellar ataxia, with symptoms depending on the disease's repeat size and duration, primarily studied in a large cohort of Indian patients.
- In a study of 100 genetically confirmed FRDA patients, most had symptoms starting between ages 5-25, with gait ataxia, loss of proprioception, and areflexia being universal symptoms.
- Additional complications observed included dysarthria and sensory polyneuropathy, while imaging revealed cerebellar and cord atrophy in half of the patients, highlighting the need for awareness about the various manifestations of FRDA.