Publications by authors named "Ram Sundar"
Article Synopsis
- The study aimed to update the National Institute for Health and Care Excellence (NICE) guidelines on brain imaging for non-small cell lung cancer (NSCLC) using real-world data from 444 patients in the UK instead of previous modeled assumptions.
- Real-world findings showed lower rates of occult brain metastases than NICE had reported, and a significantly higher percentage of patients with stage III NSCLC completed their planned treatment, indicating better outcomes than previously assumed.
- The analysis concluded that while brain imaging is cost-effective for stage III NSCLC treatment, it is not cost-effective for stage II, challenging the previous NICE recommendations for this group.
Introduction: Treating tobacco dependency in patients admitted to acute care National Health Service (NHS) trusts is a key priority in the NHS 10-year plan. This paper sets out the results of a health economic analysis for 'The CURE Project' pilot; a new hospital-based tobacco dependency service.
Methods: A health economic analysis to understand the costs of the intervention (both for the inpatient service and postdischarge costs), the return on investment (ROI) and the cost per quality-adjusted life year (QALY) of the CURE Project pilot in Greater Manchester.
Introduction: The current study aims to identify enablers and barriers to implementing smoke-free NHS hospital grounds through a hospital staff survey.
Methods: Staff members from eight acute care NHS trusts in Greater Manchester were invited to complete a 15-minute web-based questionnaire.
Results: Five-hundred and eighty-eight participants completed the questionnaire.
Introduction: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a pivotal test in lung cancer staging and diagnosis, mandating robust audit and performance monitoring of EBUS services. We present the first regional cancer alliance EBUS performance audit against the new National EBUS specification.
Methods: Across the five EBUS centres in the Greater Manchester Cancer Alliance, data are recorded at the point of procedure, when pathological results are available and at 6 months postprocedure to review any further pathological sampling (eg, at surgical resection) and the outcome of clinical-radiological follow-up.
The COVID-19 pandemic has been a disruptive event for cancer patients, especially those with haematological malignancies (HM). They may experience a more severe clinical course due to impaired immune responses. This multi-center retrospective UK audit identified cancer patients who had SARS-CoV-2 infection between 1 March and 10 June 2020 and collected data pertaining to cancer history, COVID-19 presentation and outcomes.
View Article and Find Full Text PDFObjective: To evaluate the role of continuous positive air pressure (CPAP) in the management of respiratory failure associated with COVID-19 infection. Early clinical management with limited use of CPAP (3% of patients) was compared with a later clinical management strategy which had a higher proportion of CPAP use (15%).
Design: Retrospective case-controlled service evaluation for a single UK National Health Service (NHS) Trust during March-June 2020 designed and conducted solely to estimate the effects of current care.
Introduction: The reported incidence of JE among patients with acute encephalitic syndrome (AES) in Nepal ranges between 20% to 62%. In light of the lack of up-to-date data, we sought to describe the epidemiology of JE in Chitwan, Nepal.
Methods: A prospective observational study was conducted during 2010-2012 in the College of Medical Science in the Chitwan District.