Graphitic Carbon Cloth-Based Hybrid Molecular Catalyst: A Non-conventional, Synthetic Strategy of the Drop Casting Method for a Stable and Bifunctional Electrocatalyst for Enhanced Hydrogen and Oxygen Evolution Reactions.

Hydrogen energy production through water electrolysis is envisaged as one of the most promising, sustainable, and viable alternate sources to cater to the incessant demands of renewable energy storage. Germane to our effort in this field, we report easily synthesizable and very cost-effective isoperthiocyanic acid (IPA) molecular complexes as electrocatalysts for the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) under acidic and alkaline conditions. The Pd(II)IPA, Co(II)IPA, and Ni(II)IPA complexes were synthesized and were evaluated for HER and OER applications.

Gender-specific association of TSNAX/DISC1 locus for schizophrenia and bipolar affective disorder in South Indian population.

Genetic association studies have implicated the TSNAX/DISC1 (disrupted in schizophrenia 1) in schizophrenia (SCZ), bipolar affective disorder (BPAD) and major depression. This study was performed to assess the possible involvement of TSNAX/DISC1 locus in the aetiology of BPAD and SCZ in the Southern Indian population. We genotyped seven single nucleotide polymorphism (SNPs) from TSNAX/DISC1 region in 1252 individuals (419 BPAD patients, 408 SCZ patients and 425 controls).

Duchenne muscular dystrophy: a clinical, histopathological and genetic study at a neurology tertiary care center in Southern India.

Background: Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy that affects young boys and the dystrophin gene on the X chromosome has been found to be associated with the disorder.

Materials And Methods: In this prospective study, 112 clinically diagnosed DMD patients had muscle biopsy and were tested for exon deletions. Genotyping was also carried out at STR44, STR45, STR49 and STR 50 markers in 15 families.

Paternal inheritance or a de novo mutation in a Duchenne Muscular Dystrophy pedigree from South India.

A six year old boy presented with classical features of Duchenne Muscular Dystrophy (DMD) and was confirmed by absent dystrophin staining on muscle biopsy. In the paternal line there were 5 affected individuals across two generations with classical DMD. There was no family history of the illness in the maternal line.

Serotonergic candidate genes and puerperal psychosis: an association study.

Background: Altered serotonergic function is implicated in the aetiology and pathogenesis of a host of psychiatric disorders, and structural variations/polymorphisms in genes encoding the serotonin transporter and various serotonin receptor subtypes are attractive candidates to investigate the biological component underlying these disorders. Specific phenotypic subtypes, that perhaps represent homogeneous forms of the disorder, may increase the power to detect genes in complex diseases.

Objective: We investigated regulatory and functional polymorphic DNA markers of serotonergic candidate genes using a case-control approach in puerperal psychosis and bipolar affective disorder probands.