Publications by authors named "Raluca D Ianos"
: Heart failure (HF) is one of the most common initial presentations of cardiovascular disease (CVD) in patients with type 2 diabetes mellitus (T2DM). There are different cardiac biomarkers related to the pathophysiological mechanisms of HF in T2DM. The current research aims to identify additional biomarkers that could improve the diagnosis and prognosis of HFpEF, which is currently assessed using NT pro-BNP levels.
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- Type 2 diabetes mellitus (T2DM) is a growing metabolic disorder that often leads to diabetic cardiomyopathy (DCM), a severe condition contributing to high mortality rates among diabetic patients.
- Early stages of DCM show no symptoms and have normal heart function, making it hard to detect, and current clinical markers lack specificity for early diagnosis.
- This review highlights the need for new biomarkers for early DCM diagnosis, discussing promising candidates like galectin-3 and ST2, to improve recognition and treatment outcomes.
Article Synopsis
- * The study involved 69 diabetic patients, dividing them into HFpEF (40) and non-HFpEF (29) groups, and used Receiver Operating Characteristics (ROC) curve analysis to evaluate FGF21, galectin-3, and copeptin.
- * FGF21 levels were significantly higher in HFpEF patients (mean 298.98 pg/mL) compared to non-HFpEF (mean 146.79 pg/mL), showing promise as a diagnostic