Electrical Signaling Beyond Neurons.

Neural action potentials (APs) are difficult to interpret as signal encoders and/or computational primitives. Their relationships with stimuli and behaviors are obscured by the staggering complexity of nervous systems themselves. We can reduce this complexity by observing that "simpler" neuron-less organisms also transduce stimuli into transient electrical pulses that affect their behaviors.

Perioperative hypothermia prevention: development of simple principles and practice recommendations using a multidisciplinary consensus-based approach.

Objectives: To develop a consensus on evidence-based principles and recommendations for perioperative hypothermia prevention in the Australian context.

Design: This study was informed by CAN-IMPLEMENT using the ADAPTE process: (1) formation of a multidisciplinary development team; (2) systematic search process identifying existing guidance for perioperative hypothermia prevention; (3) appraisal using the AGREE II Rigor of Development domain; (4) extraction of recommendations from guidelines meeting a quality threshold using the AGREE-REX tool; (5) review of draft principles and recommendations by multidisciplinary clinicians nationally and (6) subsequent round of discussion, drafting, reflection and revision by the original panel member team.

Setting: Australian perioperative departments.

Metabolic syndrome and surgical complications: a systematic review and meta-analysis of 13 million individuals.

Background: Metabolic syndrome (MetS) is characterised by the presence of at least three of the five following components: insulin resistance, obesity, chronic hypertension, elevated serum triglycerides, and decreased high-density lipoprotein cholesterol concentrations. It is estimated to affect 1 in 3 people around the globe and is reported to affect 46% of surgical patients. For people with MetS who undergo surgery, an emerging body of literature points to significantly poorer postoperative outcomes compared with nonaffected populations.

Nurse-led interventions among older adults affected by cancer: An integrative review.

Objective: Aging can introduce significant changes in health, cognition, function, social status, and emotional status among older adults affected by cancer. Little is known about how existing nurse-led interventions address the needs of older adults. The objective was to identify existing nurse-led interventions among older adults to optimize recovery and survivorship needs.

Experiences of participants in a clinical trial of a novel radioactive treatment for advanced prostate cancer: A nested, qualitative longitudinal study.

Objectives: Qualitative studies nested within clinical trials can provide insight into the treatment experience, how this evolves over time and where improved supportive care is required. The purpose of this qualitative study is to describe the lived experiences of men with advanced prostate cancer participating in the TheraP trial; a randomised trial of 177Lu-PSMA-617 compared with cabazitaxel chemotherapy.

Methods: Fifteen men with advanced prostate cancer were recruited from the TheraP clinical trial with interviews conducted at three timepoints during the trial.

Real-Time Event-Based Unsupervised Feature Consolidation and Tracking for Space Situational Awareness.

Earth orbit is a limited natural resource that hosts a vast range of vital space-based systems that support the international community's national, commercial and defence interests. This resource is rapidly becoming depleted with over-crowding in high demand orbital slots and a growing presence of space debris. We propose the Fast Iterative Extraction of Salient targets for Tracking Asynchronously (FIESTA) algorithm as a robust, real-time and reactive approach to optical Space Situational Awareness (SSA) using Event-Based Cameras (EBCs) to detect, localize, and track Resident Space Objects (RSOs) accurately and timely.

Identifying modifiable features of home bowel cancer screening kits to facilitate use: consumer perspectives.

Objectives: Despite the widely publicised health benefits of participation in bowel cancer screening, only 43.5% of recipients participate in the Australian National Bowel Cancer Screening Program (NBCSP). Through consultation with kit recipients, this study aimed to identify features of home bowel screening kits that could be modified to increase their use.

Neuromorphic Engineering Needs Closed-Loop Benchmarks.

Neuromorphic engineering aims to build (autonomous) systems by mimicking biological systems. It is motivated by the observation that biological organisms-from algae to primates-excel in sensing their environment, reacting promptly to their perils and opportunities. Furthermore, they do so more resiliently than our most advanced machines, at a fraction of the power consumption.

Designing Supportive e-Interventions for Partners of Men With Prostate Cancer Using Female Partners' Experiences: Qualitative Exploration Study.

Background: Partners of men living with prostate cancer (PCa) can experience a variety of unmet needs that are largely unaddressed by health care professionals. There is limited evidence to suggest which approach may be most effective in supporting partners' unmet needs and further research is required to determine how to provide support to caregivers and how technology solutions can be designed.

Objective: This study aims to explore the experience of partners of men living with PCa and their perceptions of the potential role of information technology in supporting their needs.

A health action process approach for developing invitee endorsed interventions to increase mail-out bowel cancer screening.

Theory-based, user-informed interventions are needed to increase the low participation rates of population-based faecal occult blood test (FOBT) bowel cancer screening. This study investigated the theoretical fit of the health action process approach (HAPA) for home FOBT screening and measured screening invitees' attitudes towards different intervention strategies. A cross-sectional sample (n = 377), aged 50-74 years, participated in this study.

Experiences of female partners of prostate cancer survivors: A systematic review and thematic synthesis.

The purpose of this systematic review and synthesis of studies reporting qualitative data was to understand the gendered experiences of female partners of prostate cancer survivors to inform psychosocial support for women. We searched Medline, PsycINFO, EMBASE, AMED, CINAHL, Cochrane Database of Systematic Reviews, and Sociological Abstracts for articles on 15 and 16 April 2019, and again on 30 November 2020. English language articles published in peer-reviewed journals were included if they reported solely on findings describing the perspectives of the female partners.

Photodiagnostic services in the UK and Republic of Ireland: a British Photodermatology Group Workshop Report.

Background: Photodiagnostic investigations are essential for the accurate diagnosis of abnormal cutaneous photosensitivity and provide important information for the management of patients with photodermatoses (cutaneous photosensitivity disorders). Although photodiagnosis has been undertaken since the early 1970s, specialist services in the United Kingdom (UK) and Republic of Ireland are limited and there is no formal guidance on diagnostic approach. Indeed, there is a limited literature in this area of methodology and diagnostic practice.

Event Camera Simulator Improvements via Characterized Parameters.

It has been more than two decades since the first neuromorphic Dynamic Vision Sensor (DVS) sensor was invented, and many subsequent prototypes have been built with a wide spectrum of applications in mind. Competing against state-of-the-art neural networks in terms of accuracy is difficult, although there are clear opportunities to outperform conventional approaches in terms of power consumption and processing speed. As neuromorphic sensors generate sparse data at the focal plane itself, they are inherently energy-efficient, data-driven, and fast.

Advanced prostate cancer experimental radioactive treatment-clinical trial decision making: patient experiences.

Objectives: Nested qualitative studies within clinical trials provide the opportunity to better understand participant experiences of participation and identify areas where improved support is required. The purpose of this qualitative study is to describe the lived experiences of men with advanced prostate cancer participating in the TheraP trial; a randomised trial of Lu-PSMA-617 compared with cabazitaxel chemotherapy.

Methods: Fifteen men with advanced prostate cancer were recruited from the TheraP clinical trial and interviewed at three time points during the trial.

Measuring the intensive care experience: A cross-sectional survey of patient and family experiences of critical care.

Aims And Objectives: To report patient and family intensive care experiences using the Measuring the Intensive Care Experience (MICE) tool across two intensive care units (ICU).

Background: The patient and family experience of care is an important indicator for quality improvement of ICUs, yet few studies evaluate both patient and family experiences in relation to overall care quality as well as specifically measuring quality of medical care, nursing care and organisational care as well as overall experience of the quality of intensive care.

Design: A cross-sectional survey.

Barriers to home bowel cancer screening.

Objective: To develop and test a psychometric instrument for measuring common barriers to completing and returning home bowel cancer screening kits.

Methods: One hundred and ten items were reviewed by an expert panel (n = 15) and presented in an online cross-sectional survey with 427 Australian adults. Exploratory factor analysis was used to identify an optimal factor solution of latent barrier types and aggregated factor scores were examined and compared between demographic groups.

The role of extended reality technology in healthcare education: Towards a learner-centred approach.

The use of extended reality (XR) technologies is growing rapidly in a range of industries from gaming to aviation. However, how this technology should be implemented in healthcare education is not well-documented in the literature. Learner-driven implementation of educational technology has previously been shown to be more effective than a technology-driven approach.

Are National Cancer Control Indicators for patient experiences being met in regional and remote Australia? A cross-sectional study of cancer survivors who travelled for treatment.

Objective: To examine the health services experience of patients with cancer from regional and remote Australia using the Australian National Cancer Control Indicators (NCCI) guidelines as an assessment framework.

Design: Cross-sectional.

Setting: Queensland non-for-profit cancer accommodation lodges.

Cancer-related help-seeking in cancer survivors living in regional and remote Australia.

Objectives: To measure rates of detection via screening, perceived self-imposed delays in seeking medical attention, and support seeking in a sample of regional and remote people with a cancer diagnosis and to test whether an association exists between these behaviours and minimising problems and resignation, a need for self-control and reliance and fatalism. Correlations and binary logistic regressions were conducted to test the associations between demographic characteristics, attitudes and behaviours.

Results: Females were more likely to have had their cancer detected via screening (OR = 10.

Porphyria cutanea tarda precipitated by ovarian stimulation during oocyte retrieval in a genetically susceptible female.

We report a case of 33-year-old female with underlying genetic susceptibility for familial porphyria cutanea tarda due to novel variant (c.636 + 2 dupT) unmasked by transient exposure to supraphysiological oestrogen concentrations following a single cycle of successful controlled ovarian stimulation for oocyte retrieval. Use of oral oestrogen in the form of oral contraceptive pills and hormone replacement therapy has been well known to trigger active porphyria cutanea tarda phenotype in susceptible women.

Deciding to Enrol in a Cancer Trial: A Systematic Review of Qualitative Studies.

Background: Clinical trials are essential for the advancement of cancer treatments; however, participation by patients is suboptimal. Currently, there is a lack of synthesized qualitative review evidence on the patient experience of trial entry from which to further develop decision support. The aim of this review is to synthesise literature reporting experiences of participants when deciding to enrol in a cancer clinical trial in order to inform practice.

Implementation Strategies for Interventions Aiming to Increase Participation in Mail-Out Bowel Cancer Screening Programs: A Realist Review.

Bowel cancer is the third most commonly diagnosed cancer and the third most common cause of cancer-related death, with 1,849,518 new cases of bowel diagnosed and 880,792 deaths reported globally in 2018 alone. Survival can be improved through early detection via national mail-out bowel cancer screening programs; however, participation remains low in many countries. Behavior change is therefore required to increase participation.

Community Perspectives of Complex Trauma Assessment for Aboriginal Parents: 'Its Important, but These Discussions Are Held Is Critical'.

Background And Purpose: Becoming a parent can be an exciting and also challenging transition, particularly for parents who have experienced significant hurt in their own childhoods, and may be experiencing 'complex trauma.' Aboriginal and Torres Strait Islander (Aboriginal) people also experience historical trauma. While the parenting transition is an important time to offer support for parents, it is essential to ensure that the benefits of identifying parents experiencing complex trauma outweigh any risks (e.