Cancer Integrin Imaging With 68Ga-Trivehexin PET-CT in Head and Neck Squamous Cell Carcinoma Improves Diagnostic Accuracy.

Oral squamous cell carcinoma (OSCC) is one of the most common malignancies worldwide. Locoregional nodal involvement by OSCC is commonly encountered. Current conventional and functional imaging modalities have limited diagnostic accuracy in nodal assessment, particularly in head and neck cancer.

False-Positive Radioiodine Uptake in the Cervix in a Patient with Thyroid Cancer.

Radioactive iodine (RAI) accumulation is commonly used for the detection of metastatic disease posttotal thyroidectomy. However, false-positive results have been reported due to abnormal RAI accumulation in some benign pathologies apart from metastatic sites. Here, we present one such case where false-positive I-131 uptake in the pelvis which localized to the cervix and was attributed to menstruation.

Small Chyle Leak Localized on Lymphoscintigraphy with Single-Photon Emission Computed Tomography-Computed Tomography.

Chylothorax refers to the accumulation of triglyceride-rich fluid (chyle) within the pleural space. We described a case of spontaneous chylothorax in an infant. Lymphoscintigraphy was performed with 99 m-Tc sulfur colloid which showed tracer accumulation into thoracic cavity, and single-photon emission computed tomography/CT (SPECT/CT) revealed leak in the thoracic duct at D8 vertebral level as the cause.

Recurrent Renal Cell Carcinoma Presenting as Port-Site Metastases, Detected on F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography.

The incidence of port-site metastases (PSMs) varies with the tumor type with adenocarcinoma having a high incidence. However, it is rarely seen in urological malignancies and more so in renal cell carcinoma (RCC). We hereby describe one such case of PSM after laparoscopic radical nephrectomy for RCC, which was detected on F-fluorodeoxyglucose positron emission tomography-computed tomography.

Steroid-Induced Activated White Adipose Tissue Detected on F-FDG PET/CT.

White adipose tissue (WAT) usually shows negligible F-FDG uptake due to negligible glucose utilization. However, corticosteroids alter the biodistribution of F-FDG and increase uptake in WAT. Here, we present a case of diffusely increased F-FDG uptake in WAT secondary to high-dose corticosteroid therapy for nephrotic syndrome.

Acute Myeloid Leukemia following Radioactive Iodine Therapy for Metastatic Follicular Carcinoma of the Thyroid.

Radioactive iodine (RAI) therapy is widely used and has an important role in the management of hyperthyroidism and thyroid malignancies. The development of acute or chronic leukemia is a very rare complication of RAI therapy. We report a case of metastatic Follicular thyroid cancer (FTC) who underwent total thyroidectomy followed by treatment with a cumulative dose of 1600 mCi of RAI (for 4 years) and by palliative radiotherapy for L4 spinal metastasis, later on, developed acute myeloid leukemia.

"Ebstein's Anomaly" a Potential Cause of Misinterpretation on Myocardial Perfusion Imaging.

Ebstein's anomaly is a rare congenital heart disease. We present the case of a 47-year-old woman with history of Ebstein's anomaly who was referred to nuclear medicine department for a myocardial perfusion single-photon emission computed tomography (SPECT) imaging during pre-anesthetic check-up. Myocardial SPECT perfusion images with (99mTc)-Sestamibi demonstrated medium sizes fixed perfusion defect in the mid and proximal infero-septal wall adjacent inferior wall.

An Incidentally Detected Case of Atypical Bronchial Carcinoid on Stress Myocardial Perfusion SPECT/CT.

Myocardial perfusion imaging is primarily done to look for stress-induced perfusion defects in patients suspected of having coronary artery disease. However, the rotating raw images can provide significant information on the surrounding structures. The lungs lie near the heart, and any abnormality showing increased uptake can be seen on myocardial perfusion imaging.