Automated colorimetric gadolinium assay for verification of clearance and estimation of glomerular filtration rate.

Background: NSF (nephrogenic systemic fibrosis) is a potentially serious adverse effect for renal patients undergoing MRI (magnetic resonance imaging) procedures using gadolinium-containing contrast agents. There is therefore a need to verify clearance of these agents and to confirm appropriate renal status of patients treated with these drugs.

Methods: Serum samples from canine and feline subjects dosed with 0.