Publications by authors named "Ralf Tunn"

Pain after vaginal prolapse repair surgery with mesh is generally attributed to the mesh fixation, particularly to mesh erosion, dislocation or the development of hematoma. However, once all the causes have been excluded, the urinary system, bladder and ureters should be accurately examined by means of endovaginal ultrasound. This report concerns the case of a 72-year-old woman who had undergone mesh-supported prolapse surgery 3 months prior, with no other relevant diseases, who visited the emergency department complaining of dull, right-sided colic pain.

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Introduction: Changes in surgical practice patterns to cure stress urinary incontinence (SUI) became evident after FDA warnings regarding vaginal mesh were issued. The primary aim was to describe nationwide numbers of suburethral alloplastic slings (SAS) inserted in 2010, 2015, 2018 and 2021 in Germany. Secondary, numbers were related to SUI specific non-alloplastic alternatives and bulking agents.

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Article Synopsis
  • - This revised S2k-guideline, published in December 2021, consolidates previous guidelines on female urinary incontinence, including stress and urge incontinence, and the use of ultrasonography in diagnosis.
  • - Coordinated by the German Society for Gynecology and Obstetrics, it utilized a structured consensus process involving experts from various medical fields and is aligned with the European Association of Urology's guidelines.
  • - The guideline provides comprehensive recommendations on the epidemiology, diagnosis, and treatment options for female urinary incontinence, addressing both uncomplicated and complicated cases with specific therapeutic strategies.
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Background: Pelvic floor disorders are common, especially in pregnancy and after delivery, in the postmenopausal period, and old age, and they can significantly impact on the patient's quality of life.

Methods: This narrative review is based on publications retrieved by a selective search of the literature, with special consideration to original articles and AWMF guidelines.

Results: Pelvic floor physiotherapy (evidence level [EL] 1), the use of pessaries (EL2), and local estrogen therapy can help alleviate stress/urge urinary incontinence and other symptoms of urogenital prolapse.

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Article Synopsis
  • The study aims to evaluate the differences in online health information about pelvic organ prolapse (POP) from various platforms like Google, Facebook, Instagram, LinkedIn, and YouTube to improve how patients access reliable information.
  • YouTube was found to have the most useful content, while LinkedIn featured mostly ads and misleading information, with both platforms highlighting emotional issues related to POP that are often overlooked in clinical settings.
  • Only a small percentage of websites had the Health On the Net (HON) seal, indicating they are reliable, and the overall readability of the information was found to be challenging, suggesting a need for clearer and more comprehensive online resources from professionals.
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Purpose: Obstetric anal sphincter injuries (OASIs) complicate about 5% of vaginal births. The risk of anal incontinence is increased. OASI detection rates improve with knowledge and experience.

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Objective: The international Charité-MAYO Conference aims to promote international dialog on diagnostics, management, scientific breakthroughs, and state-of-the-art surgical procedures in gynecology and gynecologic oncology and senology. Live surgeries are a fundamental tool of interdisciplinary and international exchange of experts in their respective fields. Currently, there is a controversial and emotional debate about the true value, risks, and safety of live surgical broadcasts.

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Introduction And Hypothesis: The purpose of the study was to analyze anatomical and functional outcomes after sacrocolpopexy (SCP) for vaginal vault prolapse pelvic organ prolapse quantification (POPQ) II-III by random use of absorbable (Vicryl) and non-absorbable sutures (Ethibond) for vaginal mesh fixation.

Methods: This study was designed as a two-center randomized controlled study (RCT). The primary objective was to evaluate the anatomical outcome.

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Introduction And Hypothesis: To evaluate the performance of mesh-augmented repair of anterior pelvic organ prolapse (POP) with or without apical vaginal wall involvement in women with recurrent or complex prolapse.

Methods: This multicenter cohort study included women undergoing surgery with Calistar S (Promedon, Argentina) for anterior POP between 2016 and 2018. The SCENIHR opinion was considered for patient selection, surgeon's experience and choice of implant.

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Article Synopsis
  • Urogenital fistulas are uncommon in developed countries, often resulting from surgical or radiation complications, and can be repaired using various minimally invasive techniques, with the vaginal approach being the least invasive.
  • A study analyzing 50 patients treated between 2008 and 2018 found that 96% underwent vaginal repairs with a high success rate of 96% achieved in one operation using the modified Sims-Simon technique.
  • The median surgery lasted 40 minutes with a complication rate of 14%, highlighting the effectiveness and benefits of this approach for benign gynecological fistulas.
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  • Midurethral slings are a common treatment for stress urinary incontinence, and this study compares the effectiveness of two types (TVT exact vs. RetroArc) using different insertion methods.
  • The study involved 303 women and assessed outcomes like cure rates, patient satisfaction, and complications over 3 to 12 months post-surgery.
  • Results showed that while both methods were effective, the TVT exact had better subjective outcomes compared to RetroArc, indicating that the choice of technique and material can significantly impact patient experiences.
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Purpose: It was the aim to evaluate the personal preference of mode of delivery and to analyze differences between medical professionals and non-medical professionals. Interest in participating in a risk stratification system was evaluated. We hypothesized that gaining information about risk stratification provided in the survey could potentially change participants' decision regarding the preferred mode of delivery; therefore, subjects were asked twice (before and after providing information).

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Introduction And Hypothesis: Stabilization of the vaginal apex (level 1) is an important component of operations to correct pelvic organ prolapse (POP). We report functional and anatomical results and patient-reported outcomes of our technique of vaginal vault fixation at the time of vaginal hysterectomy.

Methods: One hundred and nine patients-mean 69 years, range 50.

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Introduction: Currently, almost every third child in Germany is delivered by caesarean section. Apart from straightforward and clear indications for caesarean section which account for approx. 10%, the large proportion of relative indications in particular needs to be critically reviewed if the current C-section rate is to be effectively lowered.

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Pelvic floor protection is an issue of increasing relevance. This article sought to summarize the session at last year's annual meeting of the German Society of Gynecology and Obstetrics (DGGG) in Stuttgart (10/2016) called "Urogynecology 2020-what is the optimal rate of cesarean section-does urogynecology have to deal with Obstetrics?". The main focus was set on the two important anatomical structures, the levator ani muscle and the anal sphincters.

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Introduction And Hypothesis: To determine whether predictive parameters exist for successful duloxetine therapy in women with stress urinary incontinence (SUI).

Methods: Secondary analysis was performed of 1,714 women who received duloxetine in the Stress Urinary Incontinence Treatment (SUIT) study, a 12-month longitudinal observational study to evaluate the results and direct costs of SUI treatment. Data of 1,087 women were analyzed.

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The present study aims to introduce a transvaginal interposition of polypropylene mesh as a reproducible procedure for women with vaginal vault prolapse following cystectomy due to bladder carcinoma. No recurrent prolapse occurred in two cases 16 and 4 months after the operation. With apical fixation of the mesh, vaginal length can be maintained.

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Background And Purpose: Pelvic floor muscle training (PFMT) is an effective therapy for stress urinary incontinence (SUI). There is little and inconsistent data about different strategies of PFMT. Finding the right, patient-oriented treatment decision seems to be essential in order to achieve good results in conservative management of SUI.

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Objective: To identify women who had urinary incontinence (UI) before, during, and after pregnancy, and to determine whether women with symptoms of UI during pregnancy were the same women who had urinary incontinence postpartum.

Methods: All primigravid women who delivered within 1 year (1999) at the Charité Hospital in Berlin received a questionnaire about UI at 5 different time points during pregnancy and the postpartum period.

Results: Of 610 eligible women, 411 (67.

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Objective: To assess the cost-effectiveness of duloxetine compared with conservative therapy in women with stress urinary incontinence (SUI).

Methods: Cost and outcome data were taken from the Stress Urinary Incontinence Treatment (SUIT) study, a 12-month, prospective, observational, naturalistic, multicenter, multicountry study. Costs were assessed in UK pound and outcomes in quality adjusted life years using responses to the EuroQol (EQ-5D); numbers of urine leaks were also estimated.

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Objective: To describe the characteristics of women seeking treatment for symptoms of stress urinary incontinence (SUI) and to investigate the association of SUI symptoms with generic health-related quality of life (HRQoL) as measured by the EuroQol (EQ-5D) instrument.

Methods: The Stress Urinary Incontinence Treatment (SUIT) study was a 12-month observational study in four European countries that evaluated the cost-effectiveness of duloxetine compared with other forms of nonsurgical intervention in the treatment of the symptoms of SUI. Four hundred thirty-one physicians observed women seeking treatment for their SUI, and recorded the care provided and the outcomes of that care at enrollment and at 3, 6 and 12 months afterward The impact of SUI on baseline HRQoL as expressed by the EQ-5D index score was assessed by linear and logistic regression.

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