Normalized autofluorescence imaging diagnostics in upper GI tract: a new method to improve specificity in neoplasia detection.

Background & Aims: This study was performed to improve the autofluorescence imaging (AFI) in the upper GI tract by applying a new method of normalized autofluorescence (NAFI) obtained via tri-modal imaging.

Objective: NAFI may provide lower false positive rate to achieve ultimately better specificity at acceptable sensitivity.

Patients And Methods: This is a prospective, controlled single-centre study.