Utilization of Aryl(TMP)iodonium Salts for Copper-Catalyzed -Arylation of Isatoic Anhydrides: An Avenue to Fenamic Acid Derivatives and '-Diarylindazol-3-ones.

Herein, we report a general method for copper-catalyzed -arylation of isatoic anhydrides with unsymmetrical iodonium salts at room temperature. The developed catalytic protocol is mild and operationally simple, and aryl(TMP)iodonium trifluoroacetate is employed as the arylating partner. The methodology offers the broad applicability of both structurally and electronically diverse aryl groups from aryl(TMP)iodonium salts to access -arylated isatoic anhydrides in moderate to excellent yields (53-92%).

Metal-Free Regioselective N-Arylation of 1-Tetrazoles with Diaryliodonium Salts.

We describe a simple, metal-free regioselective N-arylation strategy for 5-substituted-1-tetrazoles with diaryliodonium salts to access 2-aryl-5-substituted-tetrazoles. Diaryliodonium salts with a wide range of both electron-rich and previously challenged electron-deficient aryl groups are applicable in this method. Diversely functionalized tetrazoles are tolerable also.

Metal-free -arylation of 5-mercaptotetrazoles and 2-mercaptopyridine with unsymmetrical diaryliodonium salts.

Herein, we demonstrate the application of unsymmetrical iodonium salts towards -arylation of heterocyclic thiols (especially tetrazole-5-thiols and pyridine-2-thiol) under metal-free conditions, affording a diverse range of di(hetero)aryl thioethers in moderate to good yields. A detailed study on the effects of counter-anions and the auxiliary of iodonium salts was conducted. Suitable auxiliary selection of the unsymmetrical iodonium salt offers flexibility for a wide range of aryl moieties and its incorporation into -arylation.

Evaluation of Genetic Diversity Based on Microsatellites and Phytochemical Markers of Core Collection of Jowitt Germplasm.

Jowitt is an industrially important crop due to its value in the aromatic, perfumery and pharmaceutical industries. In this study, 72 accessions of were selected for molecular diversity analysis using SSR markers. It revealed a total of 65 polymorphic alleles showing an average of 68.

Molecular characterization of extended-spectrum β-lactamase-producing isolated from postpartum uterine infection in dairy cattle in India.

Background And Aim: Selection and dissemination of plasmid-encoded extended-spectrum β-lactamase (ESBL) among confers resistance to beta-lactam antibiotics. The purpose of this study was to determine the prevalence and molecular characteristics of ESBL-producing organisms isolated from dairy cattle with a uterine infection.

Materials And Methods: Bacterial isolates (n=62) were characterized by biochemical test for genus and species determination.