Publications by authors named "Rakshana Ravichandran"

Non-communicable diseases (NCDs) have emerged as the predominant cause of global mortality, resulting in a substantial annual loss of human lives. Among these conditions, cardiovascular diseases (CVD) stand out as the primary cause of death. The majority of CVD cases can be attributed to certain factors that, upon modification, have the potential to significantly decrease both the incidence and severity of the disease.

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Article Synopsis
  • Cardiovascular diseases (CVD) are the leading causes of death and illness worldwide, with low social support increasing the risk and worsening outcomes for patients.
  • A systematic review analyzed five studies from 2003 to 2023, revealing a strong link between low social support and higher rates of cardiovascular events, as well as potential benefits from strong support systems.
  • Integrating social determinants of health into cardiovascular risk prediction models has been shown to enhance accuracy, yet these factors are often overlooked, emphasizing the need for their inclusion in future assessments.
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Cardiovascular disorders (CVDs) represent a global challenge and are regarded as one of the leading causes of mortality. The role of inflammation as a risk factor in these disorders has been studied, with the accelerated atherosclerotic process being a crucial factor in the pathogenesis. Several inflammatory biomarkers such as C-reactive protein (CRP), Interleukins (ILs), Tumor Necrosis Factor-alpha (TNF-α), and others have been identified that play a role in the atherosclerotic process, thus linking systemic inflammatory conditions with CVDs, including acute myocardial infarction (AMI), chronic heart failure (CHF), venous thromboembolism (VTE) and others.

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Colorectal cancer (CRC) is a rapidly escalating public health concern, which underlines the significance of its early detection and the need for the refinement of current screening methods. In this systematic review, we aimed to analyze the potential advantages and limitations of artificial intelligence (AI)-based computer-aided detection (CADe) systems as compared to routine colonoscopy. This review begins by shedding light on the global prevalence and mortality rates of CRC, highlighting the urgent need for effective screening techniques and early detection of this cancer type.

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Article Synopsis
  • There is an increasing understanding of how inflammatory bowel disease (IBD) is linked to various extraintestinal manifestations (EIMs), especially rheumatological issues like arthritis.
  • This systematic review analyzed 75 articles to evaluate the effectiveness of biological therapies for managing these rheumatic symptoms in IBD patients, focusing on eight key studies.
  • The review highlights the positive effects of biological treatments but also points out the need for continued research and the use of emerging AI technologies to improve patient care and quality of life.
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