Publications by authors named "Rakhi Mahiwall"
Article Synopsis
- End-stage liver disease (ESLD) significantly increases mortality rates, particularly when complicated by infections, which are common in these patients.
- Infections can worsen liver function and are a major cause of deteriorating health in ESLD patients.
- There is a critical need for standardized protocols for diagnosis and management of ESLD with infections, especially in the Asia Pacific region, where the prevalence is high due to factors like hepatitis B and rising cases of alcohol and NAFLD.
Severe alcoholic hepatitis (SAH) has high mortality. Dysregulated lipid transport and metabolism in liver/macrophages contributes to disease pathophysiology. Paraoxonase/arylesterase 1 (PON1), a liver-specific enzyme, inhibits oxidation of phospholipids and prevents lipid-mediated oxidative damage.
View Article and Find Full Text PDFSystemic amyloidosis of amyloid light chain associated protein (AL), also called primary amyloidosis, frequently involves the liver, but rarely causes clinically apparent liver disease. The more common presentation is with acute renal failure. Hepatomegaly and mild elevation of alkaline phosphatase are the most common clinical and biochemical findings, respectively.
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