Analyzing agreement patterns of intraoperative central nervous system lesion reporting according to type and grade.

Background: Neuropathology centers are expected to offer a prompt and accurate intraoperative diagnosis regarding tumor/lesion type and grade on fresh unfixed tissue. Level of diagnostic accuracy according to type and grade and also, the experience at a new center has not been reported before.

Aims: The aim of this study is to review the agreement patterns according to tumor/lesion type and grade between intraoperative and final histopathologic diagnosis in central nervous system (CNS) lesion samples received by a newly established neuropathology center at a tertiary care neuropsychiatric hospital.

Increased expression of Aquaporin-4 and its correlation with contrast enhancement and perilesional edema in brain tumors.

Introduction: Aquaporins and astrocytes are important in maintaining water hemostasis in brain. Upregulation of AQP-4 has been described in conditions associated with brain edema.

Aims: To study the expression of aquaporin-4 in brain tumors and its correlation with contrast enhancement and perilesional edema.

Spinal actinomycosis: a rare disease.

Actinomycosis is an indolent, slowly progressive infection caused by Actinomyces species. Of human actinomycosis, the spinal form is rare and actinomycosis-related spinal neurological deficit is uncommon. We report two cases with cervical and dorsal actinomycosis and one of them with spinal neurological deficit.

Application of domestic microwave for urgent histopathology reporting: an evaluation.

Rapid diagnosis of histopathological material is becoming increasingly desirable. In neuropathology, crush smear preparation and frozen section diagnosis of tissues removed during operative procedures, have remained as essential tools for rapid diagnosis. Microwave technology has been introduced into the field of tissue processing and staining in past decade.

Ganglioglioma of optic chiasma: case report and review of literature.

Case Report: We report a case of ganglioglioma of the optic chiasma in an 8-year-old child who presented with gradual deterioration of vision since the age of 3 years and complete loss by 8 years.

Review Of Literature: Intensive literature search by the authors showed only 12 cases of ganglioglioma involving the visual pathway reported so far. Report on our case is presented here along with review of literature.