A wideband hybrid combiner design for ITER ion cyclotron radio frequency source.

The high-power radio frequency source for ion cyclotron heating and current drive of ITER tokamak consists of two identical 1.5 MW amplifier chains. These two chains will be combined using a wideband hybrid combiner with adequate coupling flatness, phase balance, return loss, and isolation response to generate 2.

A systematic review of recent trends in research on therapeutically significant L-asparaginase and acute lymphoblastic leukemia.

L-asparaginases are mostly obtained from bacterial sources for their application in the therapy and food industry. Bacterial L-asparaginases are employed in the treatment of Acute Lymphoblastic Leukemia (ALL) and its subtypes, a type of blood and bone marrow cancer that results in the overproduction of immature blood cells. It also plays a role in the food industry in reducing the acrylamide formed during baking, roasting, and frying starchy foods.

Current Update of Phytotherapeutic Agents in the Treatment of COVID-19: Based Virtual Screening Approach for the Development of Antiviral Drug.

COVID-19, caused by the severe acquired respiratory syndrome coronavirus-2 (SARS-CoV-2), is a highly contagious disease that has emerged as a pandemic. Researchers and the medical fraternity are working towards the identification of anti-viral drug candidates. Meanwhile, several alternative treatment approaches are being explored to manage the disease effectively.

Bacterial exo-polysaccharides in biofilms: role in antimicrobial resistance and treatments.

Background: Bacterial biofilms are aggregation or collection of different bacterial cells which are covered by self-produced extracellular matrix and are attached to a substratum. Generally, under stress or in unfavorable conditions, free planktonic bacteria transform themselves into bacterial biofilms and become sessile.

Main Body: Various mechanisms involving interaction between antimicrobial and biofilm matrix components, reduced growth rates, and genes conferring antibiotic resistance have been described to contribute to enhanced resistance.

Immobilization of cellulase enzymes on nano and micro-materials for breakdown of cellulose for biofuel production-a narrative review.

Cellulose is a very abundant polymer that is found in nature. Cellulose has been used as a raw material for production of biofuels for many years. However, there are multiple processing steps that are required so that cellulose can be used as a raw material for biofuel production.

Toxicity Analysis of Recombinant L-asparaginase I and II in Zebrafish.

L-asparaginases are extensively applied in the treatment of Acute Lymphoblastic Leukemia (ALL). The treatment regime of ALL consists of asparaginase from or . The survival rate post-chemotherapy has increased to < 90% in recent years.

Performance optimization of test facility for coaxial transmission line components based on traveling wave resonator.

As part of development program for a high power co-axial transmission line component test facility, an existing traveling wave resonator based test stand is modified to improve power gain and ring return loss. The 10 dB directional coupler in the earlier test stand is replaced with a 14 dB directional coupler to couple radio frequency power with the ring. To achieve an improved isolation and return loss, the 14 dB directional coupler design is equipped with two broadside strip-lines with a tunable gap between them.

Recombinant l-Asparaginase II from subsp. ATCC 393 and Its Anticancer Activity.

l-asparaginases from bacterial origin are employed extensively in leukemic treatment and food industry. The present study focuses on the characterization of the recombinant l-asparaginase II from subsp. ATCC 393 cloned into expression system and purified using Ni-NTA chromatography.

Harmonic Scalpel-Assisted Laparoscopic Cholecystectomy vs. Conventional Laparoscopic Cholecystectomy - A Non-randomized Control Trial.

Introduction Laparoscopic cholecystectomy (LC) is the most commonly done, minimally invasive surgical procedure. Routinely used electrocautery produces more smoke, which masks the operating field, thereby prolongs the surgery and posing an increased risk of gallbladder (GB) perforation. The titanium clips used for clipping the cystic artery and cystic duct have a risk of slippage, which may lead to bleeding, and an increased risk for bile leakage.

In silico analysis, molecular cloning, expression and characterization of l-asparaginase gene from DSM 20016.

l-Asparaginase is employed in leukaemic treatment and in processing starchy foods. The in silico analysis of DSM 20016 reveals the presence of an l-asparaginase gene with theoretical pI value of 4.99.

An Unusual Cause of Small Bowel Obstruction: A Case Report.

Small bowel obstruction is a common surgical emergency. The common causes are adhesions, malignancies, and hernias. We present a rare case of small intestinal obstruction caused by an enterolith in the distal ileum in a patient with an apparently normal gut.

Functional characterization of a putative β-lactamase gene in the genome of Zymomonas mobilis.

Zymomonas mobilis ZM4 is resistant to β-lactam antibiotics but there are no reports of a β-lactam resistance gene and its regulation. A putative β-lactamase gene sequence (ZMO0103) in the genome of Z. mobilis showed a 55% amino acid sequence identity with class C β-lactamase genes.

Functional characterization of a putative endoglucanase gene in the genome of Zymomonas mobilis.

The sequence of the putative endoglucanase gene ZMO1086 in the genome of Zymomonas mobilis showed a 40% similarity with known bacterial endoglucanase genes. The upstream region of this putative gene revealed the presence of characteristic promoter (-10 and -35 regions) and a Shine-Dalgarno region. The putative endoglucanase gene was poorly expressed from the native promoter of Z.