Publications by authors named "Rajnish Budhwan"
Org Biomol Chem
September 2024
Article Synopsis
- A new environmentally friendly method for creating arylthio and arylamino compounds has been developed without the use of catalysts or metals.
- This process involves a Michael addition of arylthiols and anilines to nitroolefins and uses methanol as the solvent, eliminating the need for purification steps like recrystallization or chromatography.
- Computational studies using density functional theory are consistent with results from single crystal X-ray analysis, supporting the effectiveness of the proposed synthesis method.
Org Biomol Chem
July 2019
Article Synopsis
- - Late stage functionalization (LSF) simplifies the process of creating diverse natural products, pharmaceuticals, and agrochemicals through direct manipulation of specific chemical bonds, avoiding lengthy synthesis methods.
- - Recently, hypervalent iodine(iii) reagents have emerged as effective tools for LSF, offering easy access, mild reactions, and excellent oxidizing abilities, enabling various chemical transformations.
- - This review explores the latest progress in transition-metal-free iodine(iii) mediated direct functionalizations of heterocycles, emphasizing different synthetic methods and providing examples and mechanistic insights.
