Publications by authors named "Rajneesh Kumar Chaturvedi"
IBRO Neurosci Rep
December 2023
Article Synopsis
- The study investigates how Vitamin D3 supplementation affects gene expression related to neuroinflammation and oxidative stress in rodent models experiencing 3-NP-induced neurodegeneration, particularly focusing on immune proteins and antioxidants.
- Male C57BL/6 mice were divided into four groups, with one group receiving Vitamin D3, and gene expressions were measured using real-time polymerase chain reaction (RT-PCR). The findings revealed that Vitamin D3 significantly reduced the expression of several immune and inflammatory markers in the mice.
- The results suggest that Vitamin D3 has a neuroprotective effect in models of Huntington’s disease by lowering the gene expression linked to inflammation and improving cholinergic signaling, as evidenced by enhanced
