Modeling the impact of extreme weather events and future climate on the radiologically contaminated sites of Enewetak Atoll.

Enewetak Atoll underwent 43 historical nuclear tests from 1948 to 1958, including the first hydrogen bomb test, resulting in a substantial nuclear material fallout contaminating the Atoll and the lagoon waters. The radionuclide fallout material deposited in lagoon sediments and soil on the islands will remain for decades to come. With intensifying climate and extreme weather events, the possibility of redistribution of deposited radionuclide material has become a great concern.

Modelling the leadership characteristics for organizational readiness: a context of lean implementation in healthcare.

Purpose: The purpose of this study is to identify the leadership characteristics that make a health-care organization ready for lean implementation, analyse the interdependence among them and determine the rank of each characteristic based on their influence in the overall phenomenon.

Design/methodology/approach: The leadership characteristics were identified through a review followed by an expert interview. Then, total interpretive structural modelling (TISM) was used to analyse the interdependence and determine the rank, driving power and dependence of each characteristic.

Hydroxychloroquine in the treatment of outpatients with mildly symptomatic COVID-19: a multi-center observational study.

Background: Hydroxychloroquine has not been associated with improved survival among hospitalized COVID-19 patients in the majority of observational studies and similarly was not identified as an effective prophylaxis following exposure in a prospective randomized trial. We aimed to explore the role of hydroxychloroquine therapy in mildly symptomatic patients diagnosed in the outpatient setting.

Methods: We examined the association between outpatient hydroxychloroquine exposure and the subsequent progression of disease among mildly symptomatic non-hospitalized patients with documented SARS-CoV-2 infection.

The role of the radiation oncologist in quality and patient safety: A proposal of indicators and metrics.

This manuscript represents a collaboration from an international group of quality and safety expert radiation oncologists. It is a position/review paper with the specific aim of defining the role of the radiation oncologist in quality and safety management. This manuscript is unique in that we recommend specific quality assurance/control tasks and correlated quality and indicators and safety measures that are the responsibility of the radiation oncologist.

IAEA-HypoX. A randomized multicenter study of the hypoxic radiosensitizer nimorazole concomitant with accelerated radiotherapy in head and neck squamous cell carcinoma.

Purpose: To test the hypothesis that radiotherapy (RT) of head and neck squamous cell carcinoma (HNSCC) can be improved by hypoxic modification using nimorazole (NIM) in association with accelerated fractionation.

Materials And Methods: The protocol was activated in March 2012 as an international multicenter randomized trial in patients with HNSCC. Tumors were treated to a dose of 66-70Gy, 33-35 fractions, 6 fractions per week.

Report of chronic myeloid leukemia from Indira Gandhi Institute of Medical Sciences, Regional Cancer Center, 2002-2009.

Indira Gandhi Institute of Medical Sciences, Regional Cancer Center was established in 1993. It's one of the main Health-Care Institution in the state of Bihar. The data of 205 patients was presented in the ICON meeting and 98% of patients were diagnosed in chronic phase.

The prognostic significance of peripheral T-lymphocyte subsets and natural killer cells in patients with colorectal cancer.

Background/aims: To evaluate the prognostic significance of preoperative T-lymphocyte subsets ad natural killer (NK) cells and their correlan with other prognostic factors in patients with colorectal cancer who underwent surgical treatment.

Methodology: The numbers of T-lymphocytes and NK cells in the peripheral blood of patients with colorectal carcinoma were counted by flow cytometry, and the correlations between indicators of cellular immunity and clinicopathological characteristics and the prognosis of patients after surgical treatment were analyzed by univariate and multivariate analyses.

Results: In the multivariate regression analysis, all potential prognostic factors essentially reflected TNM stage, and tumor resection, NK lymphocyte counts, and peripheral CD3+ and CD4+/CD8+ counts were significant (p < 0.

Epidemiology of cancer: Indian scenario.

In this article the epidemiology of cancer according to the data source, burden and pattern of common cancer and its future have been described in brief in Indian scenario.

Cementing a liner into a stable cementless acetabular shell: the double-socket technique.

Background: During revision hip replacement surgery, the cementless acetabular shell is often well fixed but the locking mechanism may be ineffective. Cementing a new liner into the existing acetabular shell (the double-socket technique) can provide a simple solution. The purposes of the present study were to review our initial clinical results and to define the potential limitations of this technique.