Utility of Xpert MTB/RIF Assay for Diagnosis of Pediatric Tuberculosis Under Programmatic Conditions in India.

Tuberculosis (TB) diagnosis in children still remains a challenge in developing countries. We analyze the performance of Xpert MTB/RIF assay for the diagnosis of pediatric TB under programmatic conditions. We retrospectively analyzed the performance of Xpert MTB/RIF assay from February 2016 to March 2018.

Second-line Drug Resistance Characterization in by Genotype MTBDRsl Assay.

Tuberculosis (TB) remains a main hurdle for national programs due to increase in drug resistance to antitubercular drugs. World Health Organization (WHO)-endorsed Line Probe Assay, Genotype MTBDRsl Ver 2.0, gives opportunity for rapid diagnosis and molecular characterization of different mutations in drug targets of fluoroquinolone (FQ) and second-line injectable drugs (SLID).

Genetic Characterization of Second-Line Drug-Resistant and Extensively Drug-Resistant from the Northern Region of India.

Rapid detection of drug resistance in is important for the successful treatment of tuberculosis. Fluoroquinolone and aminoglycoside resistance detection by molecular methods becomes more complex due to cross resistance among them. Thus, we aimed to determine cross-resistance and mutations in resistance genes for these drugs.

Prevalence of Diabetes Mellitus and its Predictors among Tuberculosis Patients Currently on Treatment.

Background: Tuberculosis (TB) and diabetes are the world's leading public health issues. They are the cause of morbidity, mortality, and pose a burden on the healthcare system.

Aims And Objectives: The aim and objective of this study were to study the prevalence of diabetes and its predictors among TB patients currently on treatment.

Impact of introducing light-emitting diode fluorescence microscopy services for diagnosis of pulmonary tuberculosis under Revised National Tuberculosis Control Program India.

Context: Light-emitting diode fluorescence microscopy (LED-FM) has been recommended by the WHO and the Government of India over the conventional bright-field microscopy using Ziehl-Neelsen (ZN) staining for the diagnosis of sputum smear-positive tuberculosis (TB) suspects.

Aim: The aim of this study was to assess the effectiveness of LED-FM in detecting TB cases.

Setting And Design: This retrospective cohort study was carried out in December 2016 using secondary data of the years 2011-2012 from designated microscopy centers (DMCs) at Chandigarh, India.