Publications by authors named "Rajeswari K Avula"
Biol Psychiatry
September 2005
Article Synopsis
- Canine and murine models of narcolepsy show mutations linked to hypocretin genes, while human narcolepsy with cataplexy correlates with specific immune system markers (DQB1*0602) and low hypocretin levels, hinting at autoimmune factors.
- A study analyzed serum and cerebrospinal fluid (CSF) samples from narcoleptic and control subjects to identify IgG reactions to preprohypocretin and its cleavage products using several testing methods.
- Results found no significant IgG reactions to preprohypocretin in narcoleptic subjects, contradicting the original hypothesis that these individuals would show such immune responses.
