Hyperargininemic Encephalopathy with Unique Clinical Presentation and Novel Genetic Mutations.

Hyperargininemia is a urea cycle disorder that has rarely been reported in adults. We present a case of arginase deficiency disorder in a 32-year man with metabolic encephalopathy. He presented with progressive limb spasticity, changes in personality, cognitive decline (impaired judgement, executive and language dysfunction) and pseudo-bulbar affect.

A Novel Mutation in Neurodegeneration with Brain Iron Accumulation - A Case Report.

Neurodegeneration with brain iron accumulation (NBIA), previously called Hallervorden Spatz disease, is a group of disorders which share the hallmark of iron deposition in the brain. They are collectively characterized by extrapyramidal movement disorders, particularly those of parkinsonism, dystonia, cognitive regression, neuropsychiatric abnormalities, pyramidal features, optic atrophy, and retinal abnormalities. There is aberrant brain iron metabolism, with large amounts of iron deposited in the globus pallidus and the substantia nigra pars reticulata.

Mobile phones and seizures: drug-resistant epilepsy is less common in mobile-phone-using patients.

Background: Epilepsy is a condition where patients have seizures due to abnormal nerve impulses in the brain. The effect of mobile phone radiation on patients with seizures is not known.

Objective: To compare the seizure profile of patients not using mobile phones with that of their peers using mobile phones.

Stroke: Changing Risk Factor Profile and Unaltered Mean Age in a Developing Country. A Retrospective Study and Literature Review.

Background: The rapid changes in the lifestyles of people in the developing countries such as India are known to increase the incidence of risk factors for stroke like hypertension (HTN), diabetes mellitus and dyslipidemia. Tobacco smoking and alcoholism are on the rise. Hence, stroke might occur in younger age groups when compared to the earlier generations.