The Clinicopathological Correlation and Outcome of Glomerulonephritis With Crescent: A Single-Center Study.

Background: There is a lack of standardized treatments for patients with less than 50% crescents observed in their renal biopsies. This study aimed to analyze the crescent percentage, clinicopathological characteristics, and renal prognosis of glomerulonephritis (GN) cases with at least one crescentic lesion.

Materials And Methods: This retrospective cohort study was conducted at the Indira Gandhi Institute of Medical Sciences, Patna, from January 2016 to December 2020.

A synbiotic intervention modulates meta-omics signatures of gut redox potential and acidity in elective caesarean born infants.

Background: The compromised gut microbiome that results from C-section birth has been hypothesized as a risk factor for the development of non-communicable diseases (NCD). In a double-blind randomized controlled study, 153 infants born by elective C-section received an infant formula supplemented with either synbiotic, prebiotics, or unsupplemented from birth until 4 months old. Vaginally born infants were included as a reference group.

Growth of children with food allergies in Singapore.

Background: Although it is known that children with food allergies are at risk of impaired growth, this has not been well studied in South-East Asia.

Objective: The aim of this cross-sectional study is to survey the growth of children with food allergies in Singapore and the factors impacting it.

Methods: Anthropometric data, demographic data, type of food allergy, foods eliminated, and atopic comorbidities were recorded.

Cashew nut allergy in Singaporean children.

Background: There has been an increasing trend of nut allergies in Singapore.

Objective: The aim of this study was to review the clinical characteristics of children with cashew nut allergy.

Methods: A retrospective analysis was conducted in a tertiary paediatric referral centre in Singapore from 2008 to 2015.

Effect of Synbiotic on the Gut Microbiota of Cesarean Delivered Infants: A Randomized, Double-blind, Multicenter Study.

We determined the effect of short-chain galacto-oligosaccharides (scGOS), long-chain fructo-oligosaccharides (lcFOS) and Bifidobacterium breve M-16V on the gut microbiota of cesarean-born infants. Infants were randomized to receive a standard formula (control), the same with scGOS/lcFOS and B. breve M-16V (synbiotic), or with scGOS/lcFOS (prebiotic) from birth until week 16, 30 subjects born vaginally were included as a reference group.

A stepwise approach in the management of chronic spontaneous urticaria in children.

Background: There is limited literature in the management of chronic urticaria in children. Treatment algorithms are generally extrapolated from adult studies.

Objective: Utility of a weight and age-based algorithm for antihistamines in management of chronic spontaneous urticaria (CSU) in childhood.

Tolerance to etoricoxib in children with nonsteroidal anti-inflammatory drug hypersensitivity.

Background: Cyclooxygenase-2 (COX-2) inhibitors have been found to be safe alternatives in adults with cross-intolerant hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs). However they are usually not prescribed in children and there is little information about their tolerance in the pediatric age group.

Objective: This study aims to evaluate the tolerance to etoricoxib in children with hypersensitivity to multiple antipyretics.

Gum pigmentation: an unusual adverse effect of sublingual immunotherapy.

Sublingual immunotherapy has gained acceptance amongst the paediatric community as it is very well tolerated and is safe. The adverse effects of this therapy is minimal consisting mainly of local side effects within the oral cavity such as itching of the mouth, swelling of the lips and less frequently abdominal pain, wheezing and urticaria has been described. This report is to highlight another local side effect of sublingual immunotherapy which has been observed in 3 of our patients.

Blue-green color and composition of Stejneger's beaked whale (Mesoplodon stejnegeri) milk.

Two hundred ml of milk were obtained from a lactating Stejneger's beaked whale stranded at Ninilchik, Alaska on 21 Oct, 1980. Total solids (41%) were similar to values reported for sperm and belukha whales, while fat (17%) was half as great and crude protein (17%) was 2-4 times greater than in milk of these species. Lactose was not detected.