Publications by authors named "Rajesh K Prajapati"
Diagnostic Dilemma of Palatal Lesions: Polymorphous Adenocarcinoma (PAC) and its Insight into Updated Molecular Findings.
Indian J Otolaryngol Head Neck Surg
December 2024
Article Synopsis
- - Polymorphous AdenoCarcinoma (PAC) is a slow-growing tumor that usually develops in the minor salivary glands, especially in the palate area.
- - The case discussed involves a 52-year-old woman who presented with swelling in the palate.
- - The report focuses on the latest information regarding the molecular characteristics and immunohistochemical (IHC) findings related to PAC and its subtype, Cribriform AdenoCarcinoma with Secretory Features (CASG).
Background: Gutka chewing is the most common deleterious oral habit prevalent in the geographical distribution of the Indian subcontinent. Gutka leads to the production of numerous free radicals, which causes oxidative stress in regional oral tissues. Oxidative stress brings about the oxidation of guanine bases of DNA that generates 8-OHdG as its main byproduct.
View Article and Find Full Text PDFHybrid tumors are rare lesions having features of multiple diseases in one lesion. A hybrid tumor of central giant cell granuloma (CGCG) and central ossifying fibroma (COF) shows the presence of microscopically large areas with CGCG character and large areas with COF features inside a single clinical lesion, separated by a transition zone. A rare type of COF is juvenile ossifying fibroma (JOF)-trabecular variant in the mandible.
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