Bilateral macular retinitis as the presenting feature of subacute sclerosing panencephalitis.

Two patients presented with retinitis as the initial clinical manifestation of subacute sclerosing panencephalitis (SSPE), a delayed neurologic complication of measles. In one patient, the ocular involvement preceded the neurologic symptoms by 4 weeks and in the other patient by 4 years. The diagnosis of SSPE was suspected when neuropsychiatric manifestations appeared and was confirmed by the typical panencephalitic electroencephalography changes, neuroimaging features of panencephalitis, and high titers of measles antibodies in serum and cerebrospinal fluid.

Neuro-ophthalmic disorders presenting as a diagnostic surprise during pre-LASIK evaluation.

We present 2 cases that came to our institute for refractive surgery and were discovered to have serious systemic conditions requiring immediate intervention. On examination, prolactinoma of the pituitary gland was seen in one patient and multiple sclerosis was diagnosed in the other patient. Prompt treatment of the conditions led to improvement in the neuro-ophthalmic disorders.

Ocular manifestations associated with chikungunya.

Purpose: To report ocular manifestations associated with chikungunya.

Design: Retrospective, nonrandomized, observational case series.

Participants: Nine chikungunya patients with ocular involvement.

Clinical, anatomic, and electrophysiologic evaluation following intravitreal bevacizumab for macular edema in retinal vein occlusion.

Purpose: To investigate clinical, anatomic, and electrophysiologic response after single intravitreal injection of bevacizumab for macular edema attributable to retinal vein occlusion.

Design: Prospective nonrandomized, interventional case series.

Methods: Twenty-one patients with macular edema attributable to vein occlusion received intravitreal injection of bevacizumab 1.

Ocular tuberculosis in acquired immunodeficiency syndrome.

Purpose: To present the clinical, histopathological, and molecular biologic findings in fifteen cases of ocular tuberculosis (TB) in patients with acquired immune deficiency syndrome (AIDS).

Design: Retrospective, observational, noncomparative case series of HIV-infected patients with ophthalmic complaints and/or with advanced disease (CD4+ cell count < 200), seen between the years 1993 to 2005 at tertiary care ophthalmic and AIDS care hospitals.

Methods: Each patient underwent a complete ophthalmic examination and relevant laboratory and radiologic investigations and was treated accordingly.