Adult Onset Xantogranulomatous Disease Associated with Vitiligo.

Adult Onset Xanthogranulomatous Disease represents an umbrella term encompassing 4 distinct entities with partially overlapping clinicopathological features: adult-onset xanthogranuloma, adult-onset asthma with periocular xanthogranuloma, Erdheim-Chester disease, and necrobiotic xanthogranuloma. They are characterized by a predilection to affect the orbit and ocular adnexa and special histopathological features, in particular infiltrates comprising non-Langerhans-derived foamy histiocytes and Touton giant cells. The appearance of the eyelid lesions is virtually diagnostic, producing readily recognisable diffuse, yellow plaques.

Unilateral Blaschkoid lichen planus in successive pregnancies.

A number of genetic, congenital and acquired dermatoses have been known to follow Blaschko's lines. A common disorder like lichen planus can very rarely present with pruritic lesions in atypical patterns such as unilateral distribution, painful eruptions and along Blaschko's lines. Various triggering factors varying from viral infections and vaccinations to trauma have been implicated in lichen planus.

Autoimplantation therapy for multiple warts.

Background: In the treatment of multiple warts, there is no single treatment that is 100% effective and different modalities of treatment need to be combined.

Aim: To evaluate the efficacy of homologous autoimplantation therapy in the treatment of multiple warts.

Methods: A total of 60 patients of multiple verruca vulgaris and palmo-plantar warts were enrolled.

Recurrent herpes zoster duplex symmetricus in HIV infection.

A HIV infected patient with recurrent herpes zoster has been presented. Recurrence of herpes zoster contralaterally on the same dermatome and concomitant occurrence of three viral infections, viz. HIV, HPV and VZV in the same patient were the unusual and interesting observations in the present case report.

A comparative evaluation of skin and nerve histopathology in single skin lesion leprosy.

Background: In spite of leprosy being a disease of nerves, ROM therapy for single skin lesion leprosy was based on clinical trials without much evidence-based studies of nerve pathology. The present study was undertaken to compare the histology of skin and nerve in single skin lesion leprosy, and to assess the scientific rationale and justification of single dose ROM therapy.

Methods: Twenty-seven untreated patients with single skin lesion without significantly thickened peripheral nerves were selected.

Oral condylomata acuminata.

A case of oral condylomata acuminata in a boy aged 14 years is reported for its uncommon presentation, which warrants a high index of suspicion for diagnosis.