Publications by authors named "Rajendra K Gokhroo"

Background: Sacubitril/Valsartan (ARNI) has now class 1 recommendation for treatment of heart failure with reduced ejection fraction (HFrEF). It has been shown to reduce cardiovascular morbidity & mortality in Heart failure with reduced ejection fraction (HFrEF) and significant improvement in all echocardiographic parameters besides TEI index. Tei index is a marker of inflammation, myocardial cell metabolism and its contractile function has not been evaluated as a distinctive entity so we took up this study to evaluate the effects of ARNI on the LV functions using two dimensional (2D)ECHO parameters in Indian population and to assess TEI index for myocardial function.

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Article Synopsis
  • Ulnar artery access is gaining popularity for coronary procedures due to its lower complications compared to radial and femoral access, although success rates for radial access can be variable.
  • A study involving over 2,500 patients showed that 98.81% were successfully cannulated using ulnar access, with minimal complications such as bleeding or pulse loss.
  • Overall, ulnar access is considered a safe and feasible default strategy for patients undergoing coronary diagnostic and interventional procedures.
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Background: Atrioventricular (AV) blocks are of concern with the use of beta blockers in inferior wall myocardial infarction (MI). Ivabradine lowers heart rate with a lesser risk of AV blocks.

Objectives: To compare ivabradine with metoprolol in acute inferior wall MI in terms of feasibility, tolerability, and efficacy.

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Background: Almost all presently available pediatric echocardiography Z-score nomograms are based on Western data. They may not be a suitable reference standard for assessing the sizes of cardiac structures of children from developing countries.

Objective: This study's objective was to collect normative data of 21 commonly measured cardiovascular structures using M-mode and two-dimensional echocardiography in Indian children aged between 4 and 15 years and to derive Z-score nomograms for each.

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Submitral aneurysm is a rare structural abnormality of congenital or acquired aetiology. Most reported cases are from Africa. Unless promptly treated surgically this condition is invariably fatal.

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Background: Determining the severity of mitral stenosis (MS) is important for both prognostic and therapeutic implications. Mitral valve area (MVA) calculation techniques have more limitations. Mitral leaflet separation (MLS) is a precise and operator friendly alternative to planimetry.

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Background: Today, cardiologists seek to minimize time from symptom onset to interventional treatment for the most favorable results.

Hypothesis: In the acute coronary syndrome (ACS) symptom complex, sweating can differentiate ST-segment elevation myocardial infarction (STEMI) from non-ST-segment elevation ACS (NSTE-ACS) during early hours of infarction.

Methods: This single-center, prospective, observational study compared symptoms of STEMI and NSTE-ACS patients admitted from August 2012 to July 2014.

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Background: The association of congenital heart disease (CHD) with malformations of the gastrointestinal (GI) tract/abdominal wall is known. The rates of cardiac malformations reported in previous studies of these anomalies are highly variable.

Objective: To find the prevalence and pattern of CHD in patients with major gastrointestinal malformations (anorectal malformations, oesophageal atresia/tracheo-oesophageal fistula, and omphalocoele) undergoing surgery at a tertiary care hospital in India.

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Background: There has been an increase the acceptability and the number of the procedures via the radial approach. We present our experience pertaining to the clinical characteristics, procedural details and post procedural outcome of patients undergoing radial artery access, coronary angiographies over a period of 4 years at a primary care tertiary level center.

Materials And Methods: A retrospective analysis of all the coronary artery procedures during the last 4 years was done and the various parameters related to these procedures noted.

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Background: Anatomical obstructions are the bane of radial access site for coronary procedures for inexperienced operators. The availability of better hardware in the performance of procedures by this route has mitigated this problem. Arteria lusoria (AL) is a congenital anomaly which predisposes to access site crossover during the early phase of the learning curve.

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