Publications by authors named "Rajat Subhra Das"

The human upper limb has undergone various evolutionary myologic changes, accompanied by corresponding modifications in the anatomical course of neurovascular structures. In this study, we aimed to elucidate the emergence of the accessory head of the flexor pollicis longus (AHFPL) muscle as a beneficial biomechanical evolutionary development and its topographical relationship with adjacent neurovascular structures. In this pursuit to understand this phenomenon, dissections were conducted on sixty-two upper limbs from thirty-one cadavers.

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Variations of the lumbricals of the foot are not common, unlike the lumbricals of the hand. Few cases of unilateral absence of lumbricals of the foot have been reported. There have been far fewer cases of bilateral asymmetric absence of the lumbricals of the foot reported.

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The common carotid artery bifurcates into two terminal branches-the external and internal carotid arteries. The head, neck, and face regions principally get their blood supply from the external carotid artery and its branches. Some previous articles have mentioned the abnormal pattern of the external carotid artery branching and its variable origin.

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Essential hypertension (EH) is a significant health issue around the globe. The indifferent therapy regimen suggests varied physiological functions due to the lifestyle and genetic presentations of an individual. The endothelial nitric oxide synthase (NOS3) gene is a crucial vascular system marker in EH that contributes significantly to the phenotype.

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Article Synopsis
  • Thrombospondin-1 (THBS1) levels rise in low-oxygen (hypoxic) environments and are linked to cardiovascular issues, particularly in hypertension.
  • A study compared hypertensive individuals from high-altitude Ladakh (3500 m) and low-altitude north India (~200 m), finding that THBS1 levels were higher in the high-altitude group.
  • Genetic factors, specifically certain gene variants, were found to interact with THBS1 levels and hypertension, indicating a complex relationship between genetics and the impact of hypoxia on cardiovascular health.
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Estrogen regulates bone homeostasis and has a cardio-protective effect. Its physiological functions are mediated through receptors (ER) whose expression can be regulated by presence or absence of polymorphisms. However, the association between ER polymorphisms and BMD as well as lipids are inconsistent.

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