Publications by authors named "Rajat Kanti Sarkar"

Article Synopsis
  • The rise in allergic diseases is a significant public health issue, mainly driven by environmental and food allergens that affect breathing and digestion.
  • The lack of purified allergens for accurate diagnosis complicates the treatment and management of allergies, highlighting the need for protein-engineering techniques to create effective immunotherapy vaccines.
  • The chapter details five key allergen databases designed to provide essential molecular information, supporting researchers in the field of molecular allergology.
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Superoxide dismutases are important group of antioxidant metallozyme and play important role in ROS homeostasis in salinity stress. The present study reports the biochemical properties of a salt-tolerant Cu, Zn-superoxide from Avicennia marina (Am_SOD). Am_SOD was purified from the leaf and identified by mass-spectrometry.

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Papaya is reported to trigger food and respiratory allergy. Here, we identified chymopapain Cari p 2 as an allergen that can sensitize atopic individuals through fruit consumption followed by respiratory hazards through pollen exposure. Recombinant Cari p 2 displayed IgE-reactivity with 78% of papaya allergic sera.

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Cyclophilins are structurally conserved pan-allergens showing extensive cross-reactivity. So far, no precise information on cross-reactive IgE-epitopes of cyclophilins is available. Here, an 18-kDa IgE-reactive cyclophilin (Rhi o 2) was purified from , an indoor mold causing allergic sensitization.

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