Recent advances in platelet-rich plasma and its derivatives: therapeutic agents for tissue engineering and regenerative medicine.

Platelet rich plasma (PRP) is a suspension of bioactive factors and chemokine enriched plasma. Platelets are a distinctive source of membrane bound and soluble proteins that are released upon their activation. The higher count of platelets renders PRP with an array of tissue regenerative abilities.

A study to compare caudal levobupivacaine, tramadol and a combination of both in paediatric inguinal hernia surgeries.

Background And Aims: Caudal block is a safe and simple method of pain relief in young children with the drawback of a short duration of analgesia which can be overcome by adding various adjuvants to the injected local anaesthetic. We compared the effects of caudal levobupivacaine, tramadol and a combination of both in paediatric patients undergoing inguinal herniotomy.

Methods: A total of 78 children aged 1-7 years, planned for inguinal herniotomy were randomly allocated into three groups.