An unusual case of gunshot injury to the spine.

An eighteen-year-old male was brought with a gunshot to the right thorax. There was reduced air entry on the right chest, and the patient had AIS A neurology. However, plain radiographs of the spine were normal.

Isolated coronary artery bypass grafting in septuagenarians.

As life expectancy increases, the number of elderly patients with coronary artery disease requiring coronary artery bypass grafting (CABG) also increases. This study aims to analyse the outcomes of isolated CABG in septuagenarians. Isolated CABG patients between 70 and 79 years from January 1, 2017, to December 31, 2022, were included.

Feasibility of using chest strap and dry electrode system for longer term cardiac arrhythmia monitoring: Results from a pilot observational study.

Background And Aim: Cardiac arrhythmia diagnostic yield improves with increased duration of monitoring. We investigated patient comfort, diagnostic quality of ECG, and arrhythmia diagnostic yield using a single lead longer term external cardiac monitor (ECM).

Methods: The observational ECM feasibility study enrolled patients with increased risk of cardiac arrhythmia.

Effect of spiritual intelligence and employment status on the association between education and depressive symptoms among adults in rural Puducherry, India: A mediation analysis.

Background: Depression is a major global health concern, particularly in India, where it significantly impacts the population's well-being. The interplay of various factors, including education, employment status, and spiritual intelligence, contributes to the complex landscape of depressive symptoms among adults.

Methodology: A community-based cross-sectional study was conducted in the rural service areas of a tertiary care medical institution in rural India from March 2021 to September 2022.

Distribution and reference values of peripheral perfusion index in neonates from population-wide screening.

Background: Peripheral perfusion index (PPI) is useful in a variety of neonatal settings. Currently, available reference values are from small numbers and highly variable.

Methods: We sought to generate reference values of PPI by analysing previously collected data from newborns who underwent mandated universal pulse oximetry and PPI screening from 2018 to 2021 using uniform protocol and equipment.

Prevalence of Depressive Symptoms and Its Association with Religiosity and Spiritual Intelligence Among Adults in Rural Puducherry, India: A Community-Based Study.

Depression is a serious mental health problem globally, and its multifactorial origin and interconnections with spiritual intelligence are yet to be explored. Spiritual intelligence and religiosity are distinct concepts but share a collective goal of connecting to the divine force. This cross-sectional study (March 2021-September 2022) in rural Puducherry, India, aimed to find out the prevalence of depression and its association with spiritual intelligence and religiosity.

Surgical rescue mitral valve procedure post percutaneous transluminal mitral commissurotomy-a single-center observational study.

Percutaneous transluminal mitral commissurotomy (PTMC) has become the standard of care for severe mitral stenosis with favorable anatomy. Although the complications have reduced over the years, the need for emergency surgical rescue persists. This study evaluates the outcomes of surgical rescue performed within 24 h of undergoing PTMC from 1 January 2013 to 31 December 2019.

Evaluating Explanations From AI Algorithms for Clinical Decision-Making: A Social Science-Based Approach.

Explainable Artificial Intelligence (XAI) techniques generate explanations for predictions from AI models. These explanations can be evaluated for (i) faithfulness to the prediction, i.e.

Early Versus Standard Initiation of Terlipressin for Acute Kidney Injury in ACLF: A Randomized Controlled Trial (eTerli Study).

Background And Aims: Terlipressin infusion is effective in hepatorenal syndrome (HRS-AKI). However, its efficacy for HRS-AKI resolution in acute-on-chronic liver failure (ACLF) patients has been suboptimal. Progression of AKI is rapid in ACLF.

Extraction and characterization of fiber from the flower stalk of Sansevieria cylindrica.

A number of natural fibers are being proposed for use in composite materials, especially those extracted from local plants, especially those able to grow spontaneously as they are cost-efficient and have unexplored potential. Sansevieria cylindrica, within the Asparagaceae (previously Agavacae) family, has recently been considered for application in polymer and rubber matrix composites. However, its characterization and even the sorting out of technical fiber from the stem remains scarce, with little available data, as is often the case when the fabrication of textiles is not involved.

Reply to Berry, C. Factors Related to and Gut Physiology. Comment on "Rajan, V. An Alkaline Foregut Protects Herbivores from Latex in Forage, but Increases Their Susceptibility to Bt Endotoxin. 2023, , 2195".

The comment titled "Factors related to and gut physiology" disputes some of the inferences in the paper "An Alkaline Foregut Protects Herbivores from Latex in Forage, but Increases Their Susceptibility to Bt Endotoxin" published in this journal. The key points in the dissent are the following: 1. Bt is generally safe to non-target species.

Prevalence of common mental disorders and treatment gap among patients with non-communicable diseases in the rural areas of East India.

Background: Mental and physical non-communicable diseases (NCDs) coexist, because they share common environmental and behavioral risk factors. The treatment gap for common mental disorders, such as depression, anxiety, and substance use, is large compared to other NCDs.

Objective: To determine the prevalence and treatment gap of common mental disorders among patients with non-communicable diseases.

ASTER: A Method to Predict Clinically Relevant Synthetic Lethal Genetic Interactions.

A Synthetic Lethal (SL) interaction is a functional relationship between two genes or functional entities where the loss of either entity is viable but the loss of both is lethal. Such pairs can be used to develop targeted anticancer therapies with fewer side effects and reduced overtreatment. However, finding clinically relevant SL interactions remains challenging.

Genotyping of isolates from a tertiary care hospital in Cochin, South India.

poses a significant challenge in healthcare settings across the globe, with isolates exhibiting carbapenem resistance at unprecedented rates. Here, we characterized a collection of isolates (=64) recovered during the period September 2020 - November 2021 at a teaching hospital in Cochin, South India. The species identity of the isolates was confirmed with PCR.

Necrotizing Autoimmune Myopathy: A Case Report on Statin-Induced Rhabdomyolysis.

Statin-induced necrotizing myopathy (SINM) is an uncommon but severe complication associated with statin medication. SINM can develop at any point after a person starts taking steroids. It is now being acknowledged as a component of the broader category of "statin-induced myopathy.

An Alkaline Foregut Protects Herbivores from Latex in Forage, but Increases Their Susceptibility to Bt Endotoxin.

About 10% of angiosperms, an estimated 20,000 species, produce latex from ubiquitous isoprene precursors. Latex, an aqueous suspension of rubber particles and other compounds, functions as an antifeedant and herbivory deterrent. It is soluble in neutral to alkaline pH, and coagulates in acidic environments.

Avoiding inferior clusterings with misspecified Gaussian mixture models.

Clustering is a fundamental tool for exploratory data analysis, and is ubiquitous across scientific disciplines. Gaussian Mixture Model (GMM) is a popular probabilistic and interpretable model for clustering. In many practical settings, the true data distribution, which is unknown, may be non-Gaussian and may be contaminated by noise or outliers.

ExpertNet: A Deep Learning Approach to Combined Risk Modeling and Subtyping in Intensive Care Units.

Risk models play a crucial role in disease prevention, particularly in intensive care units (ICUs). Diseases often have complex manifestations with heterogeneous subpopulations, or subtypes, that exhibit distinct clinical characteristics. Risk models that explicitly model subtypes have high predictive accuracy and facilitate subtype-specific personalization.

Total aortic arch replacement in acute type A aortic dissection - a single institutional experience.

Aim: Total arch replacement in the presence of acute aortic dissections is one of the most challenging areas of aortic surgery. Data on outcome in the Indian scenario is sparse. The aim of this study was to assess the outcome of arch replacements in a single tertiary care center.

Tolerance of standard dose albumin infused over 6 hrs for treatment of spontaneous bacterial peritonitis-A randomized controlled trial.

Background And Aims: Twenty per cent albumin (1.5 g/kg at diagnosis and 1 g/kg on day three, infused over six-hour duration) is recommended particularly in high-risk spontaneous bacterial peritonitis (SBP). Whether reduced dose albumin infusion is as effective as the standard dose albumin infusion is not clear.

Podoplanin-positive dilated lymphatic vessels in duodenum associates with three-month mortality in patients with cirrhosis.

Dilated and dysfunctional gut lymphatic vessels (LVs) have been reported in experimental cirrhosis. Here, we studied LVs in duodenal (D2)-biopsies of liver cirrhosis patients and investigated the prognostic role of a LV marker, podoplanin (PDPN), in predicting the mortality of patients with cirrhosis. A prospective, single-center cohort study was performed in liver cirrhosis patients ( = 31) and matched healthy controls ( = 9).

Resistance profiles and genotyping of extended-spectrum beta-lactamase (ESBL) -producing and non-ESBL-producing E. coli and Klebsiella from retail market fishes.

Studies on antimicrobial resistance (AMR) profiles and epidemiological affirmation for AMR transmission are limited in fisheries and aquaculture settings. Since 2015, based on Global Action Plan on AMR by World Health Organization (WHO) and World Organization for Animal Health (OIE), several initiatives have been under taken to enhance the knowledge, skills and capacity to establish AMR trends through surveillance and strengthening of epidemiological evidence. The focus of this study was to determine the prevalence of antimicrobial resistance (AMR), its resistance profiles and molecular characterization with respect to phylogroups, antimicrobial resistance genes (ARGs), virulence genes (VGs), quaternary ammonium compounds resistance (QAC) genes and plasmid typing in retail market fishes.