Key Clinical Message: Active pemphigus vulgaris in the mother can lead to neonatal pemphigus vulgaris, which is usually self-limiting. Systemic corticosteroids are the mainstay of managing PV during pregnancy and until the child is breastfed.
Abstract: Pemphigus vulgaris (PV) is a potentially life-threatening autoimmune disease characterized by bullae and erosions over the skin and mucous membrane.
J Family Med Prim Care
August 2019
Aims And Objective: In recent period, basal cell markers high molecular weight cytokeratin (HMWCK), P63 and prostate biomarker AMACR have been used as adjuvant to morphology in diagnostically challenging cases with a very high sensitivity and specificity.
Materials And Methods: In this prospective study, total of 80 cases including 40 cases of malignant lesions and 40 cases of benign lesions of the prostate were taken. Tumor grade was determined according to Gleason's grading system.
Schwannomas are benign peripheral nerve sheath tumours that may occur throughout the body. They rarely occur in the nasal cavity. Paranasal schawannomas are uncommon lesions, representing less than 4% of all head and neck schawannomas.
View Article and Find Full Text PDFNasal natural killer/T cell lymphomas are locally destructive mid-facial necrotizing lesions. It is an uncommon disease but, usually shows a highly aggressive clinical course. Amongst the sino-nasal lymphomas, it is the most common type.
View Article and Find Full Text PDFIndian J Hematol Blood Transfus
September 2014
Hemophagocytic syndrome is a life threatening condition characterized by uncontrolled hyperinflammation on the basis of various inherited or acquired immune deficiencies. We report a case of hemophagocytic syndrome in a 18 years old male with a brief review of literature.
View Article and Find Full Text PDFThe ancient schwannoma is a rare variant of a neurilemoma with a course typical of a slow-growing benign neoplasm. Histologically, it can be confused with a malignant mesenchymal tumor because of increased cellularity, nuclear pleomorphism, and hyperchromatism. Despite the degree of nuclear atypia, mitotic figures are absent.
View Article and Find Full Text PDFPure mucinous carcinoma of the male breast is an uncommon malignant breast neoplasm and extremely rare is its metastasis in axillary lymph nodes. Most of these cases have been diagnosed after surgical resection with only a few cases diagnosed on fine needle aspiration cytology (FNAC). Although FNAC is well established in the evaluation of breast masses in females there are few reports in males.
View Article and Find Full Text PDFPrimary malignant melanoma of cervix is a rare entity. A case of primary malignant melanoma of cervix presented with vaginal discharge and black colored growth over cervix. Histology showed malignant pleomorphic cells with melanin pigment in the cytoplasm.
View Article and Find Full Text PDFTwo distinct patterns of reinnervation occur after injury to the cutaneous nerves: regenerative growth of the injured nerve and "collateral sprouting" of neighboring intact nerves. We describe two complementary models of regrowth of transected small sensory fibers in human skin. The "incision" model uses a circular incision that transects the subepidermal plexus, resulting in Wallerian degeneration of the nerve fibers that enter the incised cylinder, leaving a defined zone of denervated dermis and epidermis.
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