Treatment of dry eye: an analysis of the British Sjögren's syndrome association comparing substitute tear viscosity and subjective efficacy.

Purpose: This study aims to address the lack of independent subjective efficacy data on artificial tear substitutes in the treatment of dry eye due to the anecdotal association of 'thicker' products being more effective.

Methods: This is an independent study of the subjective use and efficacy of topical treatments used by members of the British Sjögren's Syndrome Association (BSSA) related to product viscosity. 2000 members of the BSSA were sent a questionnaire regarding their physical condition and the use of artificial tear substitutes.

Clinical review of periorbital capillary hemangioma of infancy.

Purpose: To explore the role of intralesional steroid injections (ILSI) and oral steroids in the management of periocular hemangioma of infancy (HOI).

Methods: In this retrospective study, treatment options studied were observation, ILSI, and oral steroids. All children received adjunctive amblyopia treatment if required.

Presumed early-onset sarcoidosis: a case of devastating ocular inflammation in an infant.

Involvement of the orbit and posterior segment of the eye in early-onset sarcoidosis may necessitate prompt and aggressive immunosuppressive treatment to prevent a poor visual outcome.

Blepharokeratoconjunctivitis in Cockayne syndrome.

Cockayne syndrome is a multisystemic, autosomal recessive disease resulting from abnormalities of DNA repair. Ocular manifestations are common, particularly congenital cataract and retinal dystrophy. This study describes a previously unreported association of blepharokeratoconjunctivitis (BKC) in Cockayne syndrome.

A 10-year follow up of ocular hypertensive patients within the Bolton Corneal Thickness Study. Can measured factors predict prognostic outcomes?

Objective: This is a case note review of a cohort of patients examining the effects of central corneal thickness (CCT), presenting intraocular pressure (IOP), age and gender on the risk of progression of ocular hypertension (OHT) to primary glaucoma (POAG) over a 10-year period.

Design: Cohort study with retrospective case note review.

Participants And Methods: 58 case notes from a cohort at the Bolton Royal Infirmary initially assessed 10 years ago were reviewed again.

Standards in consent for cataract surgery.

Consent forms for cataract surgery performed at Burnley General Hospital (BGH) and Blackburn Royal Infirmary (BRI) from October 4 to December 7, 2004, were prospectively reviewed to ensure that the East Lancashire Hospital's National Health Service (NHS) Trust Policy on consent to treatment and Department of Health (DoH) guidelines were being followed when seeking consent for cataract surgery. A set of 22 criteria derived as standards were formulated from the reference guide published by the DoH and from the East Lancashire trust policy document for consent to treatment. Each consent form was measured against these standards.

Assessment of the biomechanical properties of the cornea with the ocular response analyzer in normal and keratoconic eyes.

Purpose: To compare hysteresis, a novel measure of ocular rigidity (viscoelasticity) in normal and keratoconic eyes.

Methods: The study consisted of 207 normal and 93 keratoconic eyes. Eyes were diagnosed as keratoconic based on clinical examination and corneal topography.

Diurnal variation of ocular hysteresis in normal subjects: relevance in clinical context.

Background: This study was conducted to assess the diurnal variation in ocular hysteresis, as measured by the Ocular Response Analyser to establish a relationship between diurnal hysteresis variation and diurnal intraocular pressure (IOP) variation.

Methods: Forty-two normal eyes of 21 colleagues and staff in a teaching hospital in Birmingham, UK, were recruited. The IOP and hysteresis were measured by the Ocular Response Analyser.

Sequestered viscoelastic after deep lamellar keratoplasty using viscodissection.

Purpose: Deep lamellar keratoplasty (DLKP) is an intricate procedure that preserves the host's endothelium, thus eliminating the possibility of endothelial graft rejection and potentially offering great benefits over penetrating keratoplasty. DLKP may be performed by a variety of techniques including viscodelamination, in which the stroma is separated from Descemet's membrane using viscoelastic.

Methods: Here we present an operative complication of this technique, which was not initially recognized, that caused significant morbidity to our patient and eventually led to the eye requiring a full thickness regraft.