5-Hydroxymethylfurfural-Derived Boron-Dipyrromethene Immobilized on Resin Support as a Sustainable Catalyst for C-H Arylation of Heterocycles.

5-Hydroxymethylfurfural (HMF) was used as a sustainable raw material in the development of a resin-supported boron-dipyrromethene (BODIPY)-based photocatalyst. In the development of the catalyst, the brominated product (HMF-BODIPY-Br) and photocatalyst (HMF-BODIPY-Br-Suc) were isolated under a chromatography-free condition. The photocatalyst was loaded on polymeric resin by bridging alcohol functionality in HMF and amine functionality in polymeric resin using succinic anhydride.

Simple admixture of 4-nitrobenzaldehyde and 2,4-dimethylpyrrole for efficient colorimetric sensing of copper(II) ions.

An easily accessible chemo-probe based on physical mixture of 2,4-dimethylpyrrole and 4-nitrobenzaldehyde has been developed. Based on NMR spectroscopic analysis, catalyst free formation of dipyrromethane was observed in the physical mixture of chemo-probe. The probe is utilized in effective colorimetric sensing of copper(II) ions present in environmental solutions by instantaneous appearance of red colour, even in the co-existence of various metal ions.

A Glutathione-Responsive Short Sequence of Metal-Organic Complex Array.

A short metal-organic complex array (MOCA) containing a sequence of RPtRRu (1 ) was found to exhibit unique responses to a major biothiol, glutathione (GSH). Upon binding of GSH to 1 , the resultant 1:1 complex (1 ) formed nanofibrous assemblies that suggested supramolecular polymerization through the double-salt-bridge structure formation. The binding behavior of this MOCA sequence to calf thymus DNA was also dependent on GSH; a larger conformational change of DNA was observed upon binding with 1 , relative to that with 1 .

Copper-coordination polymer-controlled Cu@N-rGO and CuO@C nanoparticle formation: reusable green catalyst for A-coupling and nitroarene-reduction reactions.

The intriguing structural properties of coordination polymers (COPs), together with the huge variety of metal ions and organic linkers to choose from, make COPs potential precursors for fabricating carbon-encapsulated metal and metal oxide nanoparticles (NPs). Herein, we have studied the role of the COP structural assembly, prepared through making subtle changes to the ligand structure, on the formation of NPs in a carbon matrix. Cu-COPs (Cu-COP-1-Cu-COP-7), generated using different amino acid-based reduced Schiff base phenolic chelating ligands, exhibited crystalline structures with differing structural organization in the solid state.

C-H oxidation and chelation of a dipyrromethane mediated rapid colorimetric naked-eye Cu(ii) chemosensor.

Copper(ii) ion mediated C-H oxidation of dipyrromethanes (DPMs) to the corresponding dipyrrins followed by complexation invoked the selective sensing of copper(ii) ions in aqueous solutions. On the addition of copper, the colour of the DPM solution instantaneously changes from yellow to pink with the detection limit of 0.104 μM measured by absorption spectroscopy, whereas visible colour changes could be observed by the naked eye for concentrations as low as 3 μM.

Gut microbial degradation of organophosphate insecticides-induces glucose intolerance via gluconeogenesis.

Background: Organophosphates are the most frequently and largely applied insecticide in the world due to their biodegradable nature. Gut microbes were shown to degrade organophosphates and cause intestinal dysfunction. The diabetogenic nature of organophosphates was recently reported but the underlying molecular mechanism is unclear.