Studying the Process of Phosphogypsum Recycling into a Calcium Sulphide-Based Luminophor.

Currently, one of the most important problems of environmental protection is the deep and complex processing of mineral raw materials. This problem is especially relevant when processing substandard ores and production waste, one of which is phosphogypsum. This study examines the process of CaSO/CaS composite material formation during the reduction of phosphogypsum with citric acid.

Investigating the association among CO2 emissions, renewable and non-renewable energy consumption in Uzbekistan: an ARDL approach.

This paper examines for the first time the relationship between CO2 emissions and the consumption of renewable and non-renewable energy in Uzbekistan, spanning the period 1985-2020. The analysis uses the Autoregressive Distributed Lags (ARDL) model to estimate the long-run dynamic multipliers and short-run elasticity coefficients of energy consumption variables. Economic factors, such as GDP, are excluded in the analysis as they may cause multicollinearity problems.

Scale-up and impact of digital and molecular diagnostic technologies on TB diagnosis and timely linkage to care in Tajikistan.

Introduction: Tajikistan is scaling up molecular diagnostic and digital technologies to strengthen its fight against drug-resistant TB (DR-TB). The study aimed to document national scale-up GeneXpert/GxAlert and Open MRS from 2012-2019 and compare time taken from TB diagnosis to treatment and quality of data recording before and after the introduction of GxAlert.

Methodology: This was a longitudinal study that included a comparison of historical cohorts.

Tuberculosis in key populations in Tajikistan - a snapshot in 2017.

Introduction: WHO End TB Strategy aims at achieving targets of 90% mortality reduction and 80% reduction in tuberculosis (TB) incidence by 2030, recommending better addressing TB and multidrug-resistant TB (MDR-TB) issues in key populations.

Aim: The study aimed at having a snapshot of the epidemiological characteristics of the key populations among the new TB patients, registered in Tajikistan during 2017.

Methodology: A cross-sectional study was conducted, using official TB registration data for all new TB case notification in Tajikistan in 2017.

Population structure of drug-resistant Mycobacterium tuberculosis in Central Asia.

Background: Drug-resistant tuberculosis (TB) is a major public health concern threathing the success of TB control efforts, and this is particularily problematic in Central Asia. Here, we present the first analysis of the population structure of Mycobacterium tuberculosis complex isolates in the Central Asian republics Uzbekistan, Tajikistan, and Kyrgyzstan.

Methods: The study set consisted of 607 isolates with 235 from Uzbekistan, 206 from Tajikistan, and 166 from Kyrgyzstan.

Capacity of Abbott RealTi MTB RIF/INH to detect rifampicin- and isoniazid-resistant tuberculosis.

Abbott RealTi MTB RIF/INH Resistance (RT RIF/INH) is a new assay for the detection of resistance to rifampicin (RIF) and isoniazid (INH) in tuberculosis (TB) patients. To evaluate the capacity of RT RIF/INH to detect resistance-associated mutations in target genes. A total of 311 strains that had been pre-characterised using genotypic methods (GenoType MTBDR, Sanger sequencing) and phenotypic drug susceptibility testing were subjected to DNA extraction on Abbott 2000 and analysed using RT RIF/INH.

Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis.

We describe 27 children and adolescents <18 years of age who received bedaquiline during treatment for multidrug-resistant tuberculosis. We report good treatment responses and no cessation attributable to adverse effects. Bedaquiline could be considered for use with this age group for multidrug-resistant tuberculosis when treatment options are limited.