Publications by authors named "Raja Muhammad Asif Khan"
Platinum(IV) prodrugs are highly promising anticancer agents because they can selectively target tumors and minimize the adverse effects associated with their Pt congeners. In this study, we synthesized dual action Pt complexes by linking oxoplatin with lithocholic acid. The synthesized compounds, designated as PL-I, PL-II, and PL-III, can spontaneously self-assemble in water, resulting in the formation of spherical shape nanoparticles.
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- Novel ultrafiltration (UF) polymer membranes were developed by mixing different amounts of a cationic polymer (PDMAEMA) into a polyethersulfone (PES) base to improve filtration efficiency and resist fouling.
- Adding PDMAEMA increased the membranes' surface energy, hydrophilicity, and porosity, leading to superior filtration performance with higher water flux and better flux recovery compared to standard PES membranes.
- Specifically, the optimized PES/PDMAEMA membrane achieved a water flux of 330.39 L·m·h, significantly outperforming the 163.158 L·m·h of the neat PES, while also reducing the total fouling ratio from 64.9% to