Publications by authors named "Raja H"

Novel species of fungi described in this study include those from various countries as follows: , from accumulated snow sediment sample. , on leaf spots of . , on submerged decaying wood in sea water, on , as endophyte from healthy leaves of .

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Introduction: The objective of this study was to assess the readability and quality of online written information on epistaxis.

Methods: The terms 'epistaxis' and 'nosebleed' were entered into Google. The first six webpages generated for each search term were screened.

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  • The study aimed to analyze how breakfast and sleep habits affect the morning attention span of health professional students, as this area is underexplored.
  • Researchers surveyed 323 undergraduate students from medical colleges in Lahore, using online questionnaires to assess their demographic info, sleep quality, breakfast habits, and self-reported attention levels during morning classes.
  • Results indicated that students who skip breakfast generally have lower attention levels, while those who eat nutritious breakfasts and get sufficient sleep perform better during morning lectures, suggesting a significant link between these habits and cognitive performance.
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Introduction: Mental health issues are being reported increasingly amongst healthcare staff and students globally. The aim of this study was to investigate the frequency of common mental health issues amongst dental faculty members at multiple institutions in Pakistan.

Methods: Following approval from the institutional ethics review board, dental faculty members at 14 dental institutions were invited to participate in an online survey based on globally validated scales for mental health problems including the Patient Health Questionnaire (PHQ-9), and the Depression, Anxiety, and Stress Scale (DASS-21).

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  • Bruxism is a disorder characterized by clenching or grinding teeth, often occurring unconsciously, and can be diagnosed using both non-instrumental (self-reporting and questionnaires) and instrumental methods (like electromyography and polysomnography).
  • The study aimed to assess whether non-instrumental diagnostic tools are reliable enough for confirming bruxism, specifically comparing these methods to more thorough instrumental diagnoses.
  • Out of 3,687 articles reviewed, only eight were deemed suitable, leading to the conclusion that non-instrumental tools alone are insufficient for a definitive diagnosis of bruxism and should be used alongside instrumental methods for better accuracy.
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  • Myocardial infarction (MI) causes significant inflammation that affects recovery, and colchicine, an anti-inflammatory drug, may help reduce adverse cardiovascular events in post-MI patients.
  • This meta-analysis reviewed randomized controlled trials to assess colchicine's effectiveness and safety, focusing on multiple cardiovascular outcomes including mortality and adverse events.
  • Results from eleven studies involving over 7,000 patients showed that colchicine significantly lowered the risk of adverse cardiovascular events and hospitalization urgency, but it also increased gastrointestinal issues without affecting overall mortality rates.
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Purpose: To evaluate the capabilities of Chat Generative Pre-Trained Transformer (ChatGPT), as a large language model (LLM), for diagnosing glaucoma using the Ocular Hypertension Treatment Study (OHTS) dataset, and comparing the diagnostic capability of ChatGPT 3.5 and ChatGPT 4.0.

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  • 53 isolates of Aspergillus section Nidulantes fungi were studied, revealing that 30 clinical isolates, including four from COVID-19 patients, were misidentified as the cryptic pathogen A. latus, which resulted from a hybridization event.
  • The research showed that A. latus displays significant genetic diversity and that both parental subgenomes are actively expressed in clinical isolates, responding to different environmental conditions.
  • Key differences in drug resistance and growth in oxidative stress were found between A. latus hybrids and related species, along with four features that could help in accurately identifying A. latus in the future.
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Alzheimer's disease (AD) is a grave illness that results in cognitive and social issues. A recent study examined the association between neuroimaging results, cognitive dysfunction, atypical cellular immune function, and poor prognostic factors in AD patients who demonstrated poor prognosis. Poor prognosis was associated with abnormal cellular immune function, extrapyramidal symptoms, altered consciousness, abnormal electroencephalogram, modified Rankin scale, increased neutrophil lymphocyte ratio, and severe pneumonia.

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Robotic-assisted devices help provide precise component positioning in conversion of unicompartmental knee arthroplasty (UKA) to total knee arthroplasty (TKA). A few studies offer surgical techniques for computed tomography (CT) based robotic-assisted conversion of UKA to TKA; however, no studies to date detail this procedure utilizing a non-CT-based robotic-assisted device. This article introduces a novel technique employing a non-CT-based robotic-assisted device (ROSA Knee System, Zimmer Biomet, Warsaw, IN) for converting UKA to TKA with a focus on its efficacy in gap balancing.

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Introduction: Septorhinoplasty addresses both functional and cosmetic concerns with the nose and has been shown to have consistent, long-term benefits for patients. Nasal irrigation and medication such as antimicrobials are prescribed postoperatively to improve outcomes. Patient compliance with these interventions and outcomes of surgery have not been described.

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Retinopathy is a group of retinal disabilities that causes severe visual impairments or complete blindness. Due to the capability of optical coherence tomography to reveal early retinal abnormalities, many researchers have utilized it to develop autonomous retinal screening systems. However, to the best of our knowledge, most of these systems rely only on mathematical features, which might not be helpful to clinicians since they do not encompass the clinical manifestations of screening the underlying diseases.

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  • Cancer is a major cause of sickness and death worldwide, but treatment methods are improving.
  • CRISPR-Cas is a powerful gene editing tool that helps researchers understand cancer better and find new ways to treat it.
  • This technology can change how cancer is treated by targeting specific genes, making traditional treatments more effective, and personalizing therapies for patients.
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  • Fungal pathogens like Aspergillus fumeigatus show strain variation in their ability to cause disease, but it's unclear if non-pathogenic relatives like Aspergillus fischeri do as well.
  • This study analyzed 16 strains of A. fischeri and found significant differences in their potential to cause harm, supported by immune response tests and mouse models.
  • Additionally, genomic analyses revealed that these strains have greater genetic diversity, with specific metabolites linked to their varying levels of virulence, highlighting the importance of studying closely related non-pathogenic species to understand fungal pathogenicity.
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Background: Despite advances in timely revascularisation of ST elevation myocardial infarction (STEMI) patients, there are several practical and unavoidable delays. Sonothrombolysis (administered during micro boluses of Perfluoropropane) initiated bedside as a point-of-care therapy during the initial evaluation of the patient may potentially mitigate this by producing early culprit vessel revascularisation.

Methods: This was a prospective, single-centre study on hemodynamically stable patients presenting within 12 hours of a first STEMI who consented for study participation.

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Introduction: Fungi biosynthesize chemically diverse secondary metabolites with a wide range of biological activities. Natural product scientists have increasingly turned towards bioinformatics approaches, combining metabolomics and genomics to target secondary metabolites and their biosynthetic machinery. We recently applied an integrated metabologenomics workflow to 110 fungi and identified more than 230 high-confidence linkages between metabolites and their biosynthetic pathways.

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The impact of cementless trabecular metal (TM) implants on implant survivorship are not well delineated. This study compares primary total knee arthroplasty (TKA) revision rates of cemented knee replacements with two cementless knee replacement designs-cementless TM and a non-TM cementless design. Data from a national registry queried TKA procedures performed for osteoarthritis from 1999 to 2020.

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Wheldone is a fungal metabolite isolated from the coculture of and , displaying cytotoxic activity against breast, melanoma, and ovarian cancer cell lines. Initially, its structure was characterized as an unusual 5-methyl-bicyclo[5.4.

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Introduction: The authors present a case of a delayed chronic subdural haematoma, a rare occurrence that manifested 3 years after a traumatic brain injury, accompanied by an unexpected symptom of urinary incontinence. Chronic subdural haematoma (CSDH) is a well-known condition characterised by the accumulation of old, liquefied blood under the dura mater, usually following minor head trauma. However, the atypical presentation of CSDH in a young patient without predisposing factors and the association with urinary incontinence challenge conventional understanding.

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Purpose: To investigate the capability of ChatGPT for forecasting the conversion from ocular hypertension (OHT) to glaucoma based on the Ocular Hypertension Treatment Study (OHTS).

Design: Retrospective case-control study.

Participants: A total of 3008 eyes of 1504 subjects from the OHTS were included in the study.

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