The Dual-Role of Benzothiadiazole Fluorophores for Enabling Electrofluorochromic and Electrochromic Devices.

Three unsymmetric fluorophores differing in their flanking electron acceptor (-NO, -CN, -CHO) were investigated for their electrofluorochromism and electrochromism. The emission yield of the -NO substituted fluorophore in the solid state was ca. 9-fold less than its -CN and -CHO counterparts.

The use of high expansion foam for stunning and killing pigs and poultry.

The EFSA Panel on Animal Health and Welfare (AHAW) was asked to deliver a scientific opinion on the use of high-expansion foam for stunning and killing pigs and poultry. A dossier was provided by the applicant as the basis for an assessment of the extent to which the method is able to provide a level of animal welfare at least equivalent to that ensured by the currently allowed methods for pigs and poultry. According to legislation, to be approved in the EU, new stunning methods must ensure (1) the absence of pain, distress or suffering until the onset of unconsciousness, and (2) that the animal remains unconscious until death.

Welfare of sheep and goats during killing for purposes other than slaughter.

Sheep and goats of different ages may have to be killed on-farm for purposes other than slaughter (where slaughter is defined as killing for human consumption) either individually (i.e. on-farm killing of unproductive, injured or terminally ill animals) or on a large scale (i.

Prevalence of Dental Caries in Tamil Nadu State, India: A Comprehensive Umbrella Analysis.

Dental caries is a major public health concern among other oral diseases in most developing and industrialized countries, particularly in those nations where preventative programs have not yet been developed. Adults and the elderly population in Tamil Nadu also face significant challenges related to dental caries beyond children and adolescents. This systematic review examined the comprehensive epidemiology of dental caries in all age groups in Tamil Nadu.

Spatial transcriptomics reveals discrete tumour microenvironments and autocrine loops within ovarian cancer subclones.

High-grade serous ovarian carcinoma (HGSOC) is genetically unstable and characterised by the presence of subclones with distinct genotypes. Intratumoural heterogeneity is linked to recurrence, chemotherapy resistance, and poor prognosis. Here, we use spatial transcriptomics to identify HGSOC subclones and study their association with infiltrating cell populations.

Epidemiology of cancer in adolescents and young adults from a tertiary care hospital in Southern India.

Purpose: This study aimed to analyze cancer pattern among adolescents and young adults (AYA) in a tertiary care center in South India.

Materials And Methods: A retrospective study was undertaken from January 2018 to December 2021 on AYA cancer patients (aged 15-39 years).

Results: Totally, 369 cases of AYA cancers were identified for analyzing the frequency and pattern of cancer distribution.

Effect of Asfotase Alfa in the Treatment of Hypophosphatasia- A Systematic Review.

Hypophosphatasia (HPP) is a life-threatening disease that occurs due to the mutation of the TNSALP (Tissue nonspecific isoenzyme of alkaline phosphatase) encoding gene. There is no approved treatment for Hypophosphatasia. Therefore, the only effective treatment for HPP is enzyme replacement therapy using the drug asfotase alfa which increases the patient's life span.

An Analysis of Gender Differences and Assessment of Oral Health Status among the General Population Residing in Kanyakumari District: A Pathfinding Scientific Study.

Aim: The aim of this study is to assess the prevalence oral health status among the general population residing in Kanyakumari district, Tamil Nadu, India.

Materials And Method: A descriptive cross-sectional study was conducted among the general public of index age groups to analyze the oral health status in the Kanyakumari district. A total number of 400 samples were selected and were equally divided among urban (200 samples) and rural areas (200 samples).

Therapeutic Use of Anti-Sclerostin Antibody in the Treatment of Multiple Myeloma: A Systematic Review.

Multiple myeloma is a malignant cancerous condition that is characterized by abnormal plasma cell production and can lead to bone destruction due to increased osteoclastic activity and decreased osteoblastic activity. Many therapeutic therapies are used to treat diseases, such as chemotherapy and radiotherapy. In recent years, anti-sclerostin antibody treatment has been under investigation for its effect on the multiple myeloma.

Effect of Fluoride on Oral Health Status Among General Population Residing in High- and Low-Level Fluoride Blocks in Erode District, Tamil Nadu, India: A Cross-Sectional Study.

Aim: The aim of this study was to evaluate the fluoride levels in groundwater and their effect on oral health status among the general population of Erode district, Tamil Nadu, India.

Materials And Methods: A descriptive cross-sectional study was conducted among the general population of index age groups 5, 12, 15, 35-44, and 65-74 years. A total of 540 subjects participated in the study.

Association of tobacco exposure with demographic and clinicopathological factors in patients of oral squamous cell carcinoma - A single-center experience.

Introduction: Almost a third of the global load of oral squamous cell carcinoma (OSCC) occurs in India and can be attributed to the widespread use of tobacco and tobacco-related products in this part of the sub-continent.

Materials And Methods: Records of 274 patients of OSCC treated between January 2018 and December 2019 in our institute were analyzed for the study for history of tobacco abuse and distribution of associated demographic, clinical, and pathological factors.

Results: The age of the patients in the study ranged from 31 to 82 years with a median age of 60 years.

Facile construction of cost-effective zinc-aluminium polymeric framework for efficient removal of selective both drug and dye from an aqueous medium.

A novel aluminium (Al) and its active alloys are extensively been used in nearly all areas owing to their cost-effectiveness. But when it is subjected to an aqueous medium, gets corroded through a chemical response. In this paper, a novel framework was fabricated by copolymer coating over on Al and loaded with zinc via electro polymerization and electrodeposition method ([EDA- OPDA]Al@Zn).

Safety and efficacy of a feed additive consisting of CNCM I-5642 (PP102I) for cats and dogs (Nestlé Enterprises S.A.).

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of CNCM I-5642 (PP102I) when used as a feed additive for cats and dogs. The product under assessment consists of viable cells of a strain of , a species considered suitable for the qualified presumption of safety (QPS) approach to safety assessment. The strain was unambiguously identified as and was shown not to harbour antimicrobial resistance determinants for antibiotics of human and veterinary importance, thus meeting the QPS requirements.

An intrinsically stretchable and bendable electrochromic device.

Stretchable electrochromic devices (ECDs) were fabricated from electrospun PEDOT:PSS (poly(3, 4-ethylenedioxythiophene):polystyrene sulfonate) fibers. Stretchable and transparent electrodes with a sheet resistance of 1200 Ω sqwere prepared by depositing the conductive fibers on elastomeric substrates that were prepared from polydimethylsiloxane. The conductive substrates replaced the ITO coated glass electrodes that are typically used in ECDs.

Processing of Aluminium-Silicon Alloy with Metal Carbide as Reinforcement through Powder-Based Additive Manufacturing: A Critical Study.

Powder-based additive manufacturing (PAM) is a potential fabrication approach in advancing state-of-the-art research to produce intricate components with high precision and accuracy in near-net form. In PAM, the raw materials are used in powder form, deposited on the surface layer by layer, and fused to produce the final product. PAM composite fabrication for biomedical implants, aircraft structure panels, and automotive brake rotary components is gaining popularity.

Bio-Fabrication of Human Amniotic Membrane Zinc Oxide Nanoparticles and the Wet/Dry HAM Dressing Membrane for Wound Healing.

The preparation of unique wet and dry wound dressing products derived from unprocessed human amniotic membrane (UP-HAM) is described. The UP-HAM was decellularized, and the constituent proteins were cross-linked and stabilized before being trimmed and packed in sterile Nucril-coated laminated aluminium foil pouches with isopropyl alcohol to manufacture processed wet human amniotic membrane (PW-HAM). The dry type of PD-HAM was prepared by decellularizing the membrane, UV irradiating it, lyophilizing/freeze-drying it, sterilizing it, and storing it at room temperature.

Spatial confinement alters the ultrafast photoisomerization dynamics of azobenzenes.

Ultrafast transient absorption spectroscopy reveals new excited-state dynamics following excitation of -azobenzene (-Az) and several alkyl-substituted -Az derivatives encapsulated in a water-soluble supramolecular host-guest complex. Encapsulation increases the excited-state lifetimes and alters the yields of the → photoisomerization reaction compared with solution. Kinetic modeling of the transient spectra for unsubstituted -Az following nπ* and ππ* excitation reveals steric trapping of excited-state species, as well as an adiabatic excited-state → isomerization pathway for confined molecules that is not observed in solution.

Dynamics of Anthracene Excimer Formation within a Water-Soluble Nanocavity at Room Temperature.

Excited anthracene is well-known to photodimerize and not to exhibit excimer emission in isotropic organic solvents. Anthracene (AN) forms two types of supramolecular host-guest complexes (2:1 and 2:2, H:G) with the synthetic host octa acid in aqueous medium. Excitation of the 2:2 complex results in intense excimer emission, as reported previously, while the 2:1 complex, as expected, yields only monomer emission.

Is Individual deprivation measures associated with dental anxiety and socioeconomic status of patients visiting dentists.

Aim: To assess the association between Individual deprivation measure with dental anxiety and socioeconomic status among patients visiting dentists in Chennai city, Tamil Nadu.

Methods: A cross-sectional study was conducted among 50 patients aged 18-70 years who visited a private dental institution. Data on socio-demographics and detailed history about dental visits were obtained.

Remote electron and energy transfer sensitized photoisomerization of encapsulated stilbenes.

Excited state chemistry and physics of molecules, in addition to their inherent electronic and steric features, depend on their immediate microenvironments. This study explores the influence of an organic capsule, slightly larger than the reactant molecule itself, on the excited state chemistry of the encapsulated molecule. Results presented here show that the confined molecule, in fact, is not isolated and can be manipulated from outside even without direct physical interaction.

Prediction of recurrence based on the patellofemoral morphological profile and demographic factors in first-time and recurrent dislocators.

Introduction: Prediction of recurrence in first-time patellar dislocation is an unsolved mystery. The purpose of our study is to compare patellar instability patients and normal control groups with anatomical risk factors and validation of newer parameters patello-trochlear index (PTI) and tibial tuberosity-posterior cruciate ligament (TT-PCL) and also to find the significant risk factors that help to predict the recurrence of dislocation in first-time dislocators.

Methods: This is a comparison study between 50 normal individuals as a control population (group-1) and 94 patients with patellar instability done between 2013 and 2017.

Perceived oral health beliefs, traditional practices, and oral health status of nomads of Tamilnadu: A cross-sectional study.

Aim: To assess the perceived oral health beliefs, traditional practices, and oral health status of nomads.

Methods: A cross-sectional study was conducted among 115 nomads residing in various places of Tamilnadu. Information regarding socio-demographics such as age, gender, occupation, and place of residence were obtained.

Acetaminophen micropollutant: Historical and current occurrences, toxicity, removal strategies and transformation pathways in different environments.

Acetaminophen (ACT) is commonly used as a counter painkiller and nowadays, it is increasingly present in the natural water environment. Although its concentrations are usually at the ppt to ppm levels, ACT can transform into various intermediates depending on the environmental conditions. Due to the complexity of the ACT degradation products and the intermediates, it poses a major challenge for monitoring, detection and to propose adequate treatment technologies.

Reversal of Regioselectivity during Photodimerization of 2-Anthracenecarboxylic Acid in a Water-Soluble Organic Cavitand.

The value of octa acid (OA) as a reaction vessel in steering a photoreaction toward a less favored product was established. Photodimerization of 2-anthracenecarboxylic acid within OA yields exclusively dimers, while in media such as solution, cyclodextrins (CD) and related hosts yield predominantly dimers. Further, OA enhances the chiral selectivity on the product dimers.