Efficacy of repetitive transcranial magnetic stimulation for phantom limb pain- a meta analysis of randomized controlled trials.

Introduction: Phantom limb pain (PLP) is a neuropathic syndrome experienced by the majority of amputees. Various treatment options are available for amputees suffering from PLP including pharmacological, psychological and neuromodulation techniques. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation technique that has proven its efficacy in alleviating PLP.

Neurodevelopmental outcomes after infant heart surgery for congenital heart disease: a hospital-based multicentre prospective cohort study from India.

Background: Neurodevelopmental disability is a common long-term concern following surgery for congenital heart disease (CHD). Little information is available from low-resource environments where the majority of children with CHD are born. Several challenges in the CHD care continuum exist in such environments.

Prevalence and genomic insights of carbapenem resistant and ESBL producing Multidrug resistant Escherichia coli in urinary tract infections.

Urinary tract infections are a common condition affecting people globally, with multidrug-resistant (MDR) Escherichia coli (E. coli) being a major causative agent. Antimicrobial susceptibility profiling was performed using the VITEK 2 automated system for 1254 E.

Neonatal outcomes in offspring of mothers with pregestational diabetes: a hospital-based multicentre prospective cohort study protocol.

Introduction: Pregestational diabetes mellitus (PGDM) occurs when a woman becomes pregnant after having diabetes mellitus. The presence of diabetes during the entire pregnancy can have an adverse impact on fetal and neonatal outcomes. The objective of this study is to examine the association between PGDM and neonatal outcomes at birth.

Unveiling predictors of developmental delay among under-fives: Insights from a community study.

Introduction: The development of a child is a crucial factor that ultimately affects the quality of life of children. Developmental delay can be prevented if it is identified early and adequate attention is given from the start.

Methodology: A cross-sectional analytical study was conducted between December and November 2022 on 450 children by multistage cluster sampling in the Ormanjhi block of Ranchi, Jharkhand.

Bilateral Traumatic Rupture of the Quadriceps Tendon - A Case Report.

Introduction: Quadriceps tendon rupture is a traumatic injury where the quadriceps detaches from the patella, disrupting the knee's extensor mechanism. Bilateral ruptures, first documented in 1949, are rare, with an incidence of 0.17-2.

Research Trends in the Management of Scaphoid Non-unions: A Bibliometric Review.

Background: The scaphoid is the most commonly fractured carpal bone, often going into non-union and secondary complications. Despite this, no explicit guidelines exist for the management of its non-union till date. This study quantitatively analyses the existent research on scaphoid nonunions from 2013 to 2024 using bibliometric methodology.

Decoding the Catalytic Potential of Dinuclear 1-Row Transition Metal Complexes for Proton Reduction and Water Oxidation.

The growing interest in renewable energy sources has led to a significant focus on artificial photosynthesis as a means of converting solar energy into lucrative and energy-dense carbonaceous fuels. First-row transition metals have thus been brought to light in the search for efficient and high-performance homogenous molecule catalysts that can accelerate energy transformation and reduce overpotentials during the catalytic process. Their dinuclear complexes have opportunities to enhance the efficiency and stability of these molecular catalysts, primarily for the hydrogen evolution reaction (HER) and water oxidation reaction (WOR).

Impact of exposure to extreme heat events during pregnancy on the incidence of congenital heart disease in offspring: a meta-analysis.

Background: The aetiology of congenital heart disease (CHD) is multifactorial. Environmental risk factors have emerged as an important modifiable determinant of several congenital cardiac conditions. Previous studies have shown a strong relationship between CHD and air pollution.

Changes in Caregivers' Use of the Online Medical Record Pre- and Post-COVID: Analysis of the Health Information National Trends Survey, 2018-2022.

Little is known about online medical record (OMR) use among caregivers, including changes in OMR use through the COVID-19 pandemic. This study compares OMR use among caregivers and non-caregivers before and during the COVID-19 pandemic, identifies reasons for non-use, and examines the association between caregiving status and characteristics with OMR use. Secondary data analysis of the nationally representative Health Information National Trends Survey data from 2018 to 2022 ( = 14,034).

Prospective cohort study exploring the neurodevelopmental outcomes following documented neonatal sepsis in Nepal: study protocol.

Introduction: Neonatal sepsis, a significant contributor to global neonatal mortality, poses substantial risks to infant health, particularly in low-resource countries like Nepal. Despite its high prevalence, there is a lack of clarity in defining and understanding neonatal sepsis, leading to challenges in diagnosing and managing the condition effectively. The probable impact of neonatal sepsis on long-term neurodevelopmental outcomes, including motor and cognitive delays, remains under-explored in Nepal.

Loneliness Among Older Caregivers: An Analysis of the 2020 California Health Interview Survey.

Aging and caregiving are each risk factors for loneliness, but little is known about loneliness among older caregivers. Using the 2020 California Health Interview Survey ( = 7638), this study examined the relationship between (1) caregiving status and loneliness among older adults; (2) sociodemographic, technology, health, and caregiving characteristics and loneliness among older caregivers; and (3) compared how these variables relate to loneliness among older caregivers of persons with dementia versus non-dementia conditions. Findings revealed that 15% of older caregivers experienced loneliness, with dementia caregiving significantly increasing this likelihood.

The Dual-Role of Benzothiadiazole Fluorophores for Enabling Electrofluorochromic and Electrochromic Devices.

Three unsymmetric fluorophores differing in their flanking electron acceptor (-NO, -CN, -CHO) were investigated for their electrofluorochromism and electrochromism. The emission yield of the -NO substituted fluorophore in the solid state was ca. 9-fold less than its -CN and -CHO counterparts.

Cost-effective synthesis of zinc oxide/crab shell-derived chitosan nanocomposite: Insights into its biomedical applications.

For biomedical applications, material scientists all over the world are working to develop cost-effective technologies and thereby synthesize new nanocomposite materials that are biocompatible, bioactive, scalable and naturally abundant. This study focuses on synthesizing and evaluating nanocomposites of zinc oxide (ZnO) and chitosan (CS) derived from crab shells, in three different weight proportions (1:0.5, 1:1, and 1:2).

Associations of Physical Activity and Sedentary Behavior With Mental Distress According to Caregiver Status: Analysis of the Health Information National Trends Survey, 2022.

Purpose: To (1) examine how physical activity and sedentary behavior are related to mental distress and (2) identify and compare how various levels of sedentary behaviors may differentially predict mental distress after accounting for physical activity, among caregivers vs non-caregivers.

Design: Cross-sectional secondary data.

Setting: National Cancer Institute's Health Information National Trends Survey Cycle 6 fielded online from March-November 2022.

Wells Syndrome: A Rare Skin Manifestation of Non-Hodgkin's Lymphoma.

Eosinophilic cellulitis, also known as Wells syndrome, presents a wide range of morphological spectrum, from pruritic erythematous papules, nodules, and pustules to urticarial and bullous lesions. This is a rare dermatological condition and is known to develop after treatment of hematological malignancy. Here, we report a case of Wells syndrome that was the initial presentation of lymphoma, preceding all other symptoms by six months.

The Effect of on Skin and Its Commensals: Contribution of Acemannan in Curing Acne Caused by .

is one of the most significant therapeutical plant species that belongs to the family Liliaceae. is composed of a high amount of water, with the remainder being dry matter. The dry matter contains a lot of bioactive compounds like carbohydrates, fats, and enzymes, with various therapeutic and antimicrobial properties.

Solvent-Dependent Chemoselectivity Switch to Arg-Lys Imidazole Cross-Links.

Herein, we report a trifluoroethanol-mediated, chemoselective method for the formation of Arg-Lys imidazole cross-links with methylglyoxal and its application in the selective macrocyclization of peptides between Lys and Arg and the late-stage diversification of Lys-containing peptides with guanidine. Our findings highlight the critical role of solvent choice in controlling chemoselectivity, providing valuable insights into solvent-dependent peptide modification.

Evaluating the Quality and Impact of TikTok Videos on Autologous Breast Reconstruction with Deep Inferior Epigastric Perforator Artery Flaps.

Background: With the rising influence of social media on healthcare perceptions, this study investigates TikTok's role in educating the public about autologous breast reconstruction, specifically focusing on deep inferior epigastric perforator flaps.

Methods: We conducted a systematic analysis of 152 TikTok videos related to deep inferior epigastric perforator flap procedures, evaluating the accuracy of the content, viewer engagement metrics, and the influence of content creator characteristics on viewer interactions.

Results: Our analysis identified a wide variance in the quality of information, with many videos lacking in-depth educational content, thereby posing a risk of misinformation.

Therapeutic effectiveness and adverse drug reactions of mirabegron versus solifenacin in the treatment of overactive bladder syndrome.

Introduction: Overactive bladder (OAB) syndrome is a chronic disease characterized by urinary urgency with or without urge incontinence, frequency, and nocturia and antimuscarinic drugs such as solifenacin have been the mainstay of treatment. Mirabegron a beta 3 adrenoreceptor agonist has recently gained importance in the management of OAB. The rationale of the study is that mirabegron improves the storage function without affecting voiding which increases the therapeutic effectiveness.