Publications by authors named "Raj Kumar Kalyan"

Introduction: Coagulase-negative (CoNS) species are normal skin commensals but may also cause bacteremia. Therefore, isolating a CoNS species on blood culture often leads to a diagnostic dilemma about whether to consider the isolate as a true pathogen or not. This study was done to understand the distribution of various CoNS species in bloodstream infections, determine their antibiotic resistance patterns, and identify possible risk factors and patient outcomes in hospital settings.

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Article Synopsis
  • The study aimed to identify and analyze the causes of joint pain related to brucellosis in patients, focusing on its symptoms of arthralgia and arthritis in northern India.
  • Conducted over two years, researchers collected 200 blood samples from patients at a hospital in Lucknow and employed various testing methods, including ELISA and PCR techniques.
  • Results indicated a small percentage of positive cases: 9.5% for anti-IgM and 11.5% for anti-IgG, with some samples testing positive for additional markers, while blood cultures yielded no infections.
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Scrub typhus, which is prevalent in the Asia Pacific region is most feared owing to its life-threatening neurological complications. We present four cases of scrub typhus with acute encephalitis, including one with multiorgan failure and another serologically proven co-infection with Hepatitis C. Treatment of scrub typhus is not, however, so difficult, so its early diagnosis is paramount.

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Background: Brucellosis is a neglected zoonotic disease affecting humans and animals.

Objectives: This study aimed to estimate the seroprevalence of brucellosis in patients with joint pain.

Methods: A total of 200 participants aged from 7 to 86 years were involved in this study.

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 Healthcare-associated urinary tract infections (HAUTIs) caused by gram-negative pathogens have emerged as a global concern. So far, little is known about the epidemiology of extended-spectrum β lactamase (ESBL)-producing and in HAUTIs in India. The study was carried to determine the antibiotic resistance pattern and ESBL-producing genes in and strains isolated from HAUTIs in a tertiary institute in North India.

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The diagnosis of Scrub Typhus is now improving with the availability of an array of serological tests at the majority of diagnostic centres and of molecular tests at advanced laboratories. Our study focuses on evaluating the spectrum of Scrub Typhus and its coinfection with Leptospirosis in patients presenting with acute febrile illness. A total of 1743 blood samples were collected from both In and Out Patient Department (OPD) patients and analyzed for anti and anti- IgM antibodies.

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Leptospirosis is considered as one of the most neglected zoonotic tropical diseases. Animals and humans acquire this infection through direct contact with contaminated urine or body fluids of infected animals. This prospective study was undertaken to know the proportion of leptospirosis in pediatric patients presented with acute febrile illness at the Post Graduate Department of Microbiology, King George's Medical University, Lucknow, Uttar Pradesh.

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Objectives: To evaluate the proportion of scrub typhus meningoencephalitis among children with acute encephalitis syndrome and to outline its differentiating features. To develop a prediction rule for scrub typhus meningoencephalitis.

Methods: A prospective cohort study was conducted at a tertiary care public hospital in Northern India.

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