[Incidence of rheumatic fever in Slovakia during the last 20 years].

The incidence of rheumatic fever has a declining trend in Slovakia. In 1972 there were 26.7 primary attacks and 8.

[Diagnosis of the causes and prevention of intrauterine fetal death in the second trimester of pregnancy in women with hyperandrogenism].

Differential diagnosis of the causes of intrauterine fetal death was carried out in 84 women; in 57 of them it was due to hyperandrogenism of various origins. 63.2% of patients suffered from mixed (combined ++ovario-adrenal) androgen hypersecretion, 33.

[Spontaneous abortions in women with androgyny].

Examinations of 1967 patients with various androgyny forms and their children have revealed the predominating role of environmental factors in the origin of reproductive function disorders in uncommon forms of androgyny. Employment of present-day informative methods of investigation, development of diagnostic criteria for the detection of various androgyny forms in patients liable to spontaneous abortions, and optimation of the therapeutic measures during pregnancy and without it help reduce the incidence of secondary sterility by four times and that of spontaneous abortions by 11 times; such measures promote prolongation of pregnancy to full-term and delivery of viable babies in 92% of the patients. Timely diagnosis and adequate pathogenetic therapy of androgyny in the mother is one of effective methods for the prevention of obstetric and gynecologic abnormalities in the offspring when adult.

[Registration of patients with chronic diseases].

The authors describe registers of chronic diseases, provisions regarding their contents and organizational aspects. They make the reader familiar with the collection, storage and evaluation of data and some problems with their safeguarding. They report their experience with recommended questionnaires and the structure of forms.

[Congenital heart defects in children born 1981-1987 in the Bratislava District and surrounding countryside].

In 1981-1987 of 61,420 liveborn children in the districts Bratislava-town and Bratislava-country 480 infants with inborn heart disease were born of whom 135 died. The mean incidence of congenital heart disease is 7.81% and the mean mortality 2.

[Breast diseases in patients with hyperandrogenism].

The study has been undertaken in 40 women with excessive androgen levels in the age range of 22 to 38 years. Various types of mastopathy were found in 34 and fatty degeneration of the glandular tissue in 6 women. On the basis of clinical and laboratory studies, the patients were assigned to 3 groups: ovarian hyperandrogenism, adrenal and ovarian-adrenal hyperandrogenism.

[The importance of rehabilitation therapy for the outcome of a subsequent pregnancy in women with spontaneous abortion and hyperandrogenism].

A complex clinical-hormonal examination was conducted in 140 women most of whom suffered from habitual abortion and hyperandrogenicity (HA). Based on the clinical findings, determination of the basal hormone level, and functional tests the patients were divided into 3 groups: 1) patients with predominantly adrenal HA (30 per cent); 2) patients with mainly ovarian HA (12.1 per cent), and 3) patients with an abnormally high level of androgens of ovarian-adrenal origin (57.

[The central register for diabetes mellitus in children in Slovakia].

The central register of diabetes mellitus in the SSR keeps records of patients from birth to the age of 14 and 18 years resp. The health institution reports patients on special forms. At the end of the first half of 1988 574 patients from the entire SSR were on record.

[State of the reproductive function in women with hyperandrogenism and miscarriage in the immediate period and long-term follow-up].

A study was made of 180 females aged 22-58 years with a history of premature labor secondary to high levels of androgen. The ovarian pattern of the disease was stated in 21 per cent (group I), mixed in 49 per cent (group II) and adrenal, in 30 per cent of examinee s (group III). In 69.