Publications by authors named "Raisa Jordana Geraldine Severino Lazo"
Prevalence of BRAF p.V600E and Detection Methods in Benign Mixed and Malignant Odontogenic Tumors: A Systematic Review.
Raisa Jordana Geraldine Severino-Lazo Marianne de Vasconcelos Carvalho Camilla Porto Campello Sandra Lúcia Dantas Moraes Belmiro Cavalcanti do Egito Vasconcelos
Head Neck Pathol
December 2023
Article Synopsis
- * A systematic review of literature was conducted, reviewing 387 records and ultimately focusing on 11 articles that met specific criteria, involving 133 patients in total.
- * The results showed that the BRAF p.V600E mutation was present in 31.42% of benign mixed tumors and 26.98% of malignant tumors, with immunohistochemistry methods showing strong agreement with DNA-based detection.
Article Synopsis
- Granular Cell Odontogenic Fibroma (GCOF) is a rare type of oral tumor, previously known by various names, and this study aims to collate and summarize existing literature on it, including a new case report.
- The review included thirty-nine studies detailing fifty-three GCOF cases, primarily affecting middle-aged women and commonly found in the back area of the mandible, with conservative treatment being the preferred method.
- There is still debate regarding the origin of GCOF, highlighting the need for further research to clarify its histogenesis and clinical behavior.