Publications by authors named "Rainer G Kozlik-Feldmann"

Article Synopsis
  • Marfan syndrome (MFS) can cause heart problems, and this study looked at how it affects children's hearts.
  • The researchers found that about 40% of kids with MFS showed signs of heart issues, even if they weren't feeling sick.
  • They discovered that certain genetic changes and higher health scores helped predict who might have heart problems in these kids.
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Article Synopsis
  • The study investigates factors affecting the durability of biological valves used in patients with tetralogy of Fallot (ToF) over a follow-up period of nearly a decade.
  • 79 patients aged 0.2 to 56.1 years underwent surgery for valve implantation, with various types of conduits being utilized.
  • Results indicate that younger age, smaller valve size, and higher z-scores are linked to decreased valve longevity, emphasizing patient age as a key factor in graft lifespan.
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Percutaneous implantation of the pulmonary valve through peripheral vascular access can be limited due to poor venous access, low patient weight, hemodynamic or rhythmic instability, and size constraints related to the valve. In such cases, hybrid procedures may provide alternatives. Because the most commonly used median sternotomy is unsuitable for chronic trials in large animals, we evaluated several hybrid approaches for pulmonary valve replacement in a swine model.

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In the summer of 2016, delegates from the German Respiratory Society (DGP), the German Society of Cardiology (DGK) and the German Society of Pediatric Cardiology (DGPK) met in Cologne, Germany, to define consensus-based practice recommendations for the management of patients with pulmonary hypertension (PH). These recommendations were built on the 2015 European Pulmonary Hypertension guidelines, aiming at their practical implementation, considering country-specific issues, and including new evidence, where available. To this end, a number of working groups was initiated, one of which was specifically dedicated to PH in adults associated with congenital heart disease (CHD).

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