Rhamnolipid enhances biofilm susceptibility, disassembly and production of virulence factors.

This study evaluated the effect of the biosurfactant rhamnolipid on the antimicrobial susceptibility, biofilm growth dynamics and production of virulence factors by . The effects of rhamnolipid on planktonic and biofilm growth and its interaction with antibacterial drugs were evaluated. Then, its effects on growing and mature biofilms and on protease and siderophore production were assessed.

Efflux pump inhibition controls growth and enhances antifungal susceptibility of species complex.

To evaluate the inhibition of efflux pumps by using promethazine (PMZ) as a strategy to control species complex (FSSC). The susceptibility of FSSC strains to PMZ and the interaction between PMZ and antifungals were evaluated. The efflux pump activity was confirmed by flow cytometry with rhodamine 6G.

Terpinen-4-ol inhibits the growth of complex and exhibits synergism with antifungal agents.

This study investigated the effect of terpinen-4-ol against complex and its interactions with antifungals. The antifungal activity of terpinen-4-ol was evaluated by broth microdilution. The potential effect on cellular ergosterol concentration was evaluated by spectrophotometry.

Chlorpromazine-impregnated catheters as a potential strategy to control biofilm-associated urinary tract infections.

This study proposes the impregnation of Foley catheters with chlorpromazine (CPZ) to control biofilm formation by , and . The minimum inhibitory concentrations (MICs) for CPZ and the effect of CPZ on biofilm formation were assessed. Afterward, biofilm formation and the effect of ciprofloxacin and meropenem (at MIC) on mature biofilms grown on CPZ-impregnated catheters were evaluated.

Proton pump inhibitors versus species: effects on susceptibility and melanin production.

This study aimed to evaluate the effects of proton pump inhibitors (PPIs) on growth and melanin production by spp. Minimum inhibitory concentrations (MICs) of omeprazole, esomeprazole, rabeprazole, pantoprazole and lansoprazole against spp. were determined and the effect of PPIs on melanin production was evaluated, in the presence or absence of copper sulfate or glutathione.

Pentamidine inhibits the growth of Sporothrix schenckii complex and exhibits synergism with antifungal agents.

Aim: The purpose of this study was to evaluate the effects of the antileishmanials meglumine antimoniate and pentamidine against Sporothrix schenckii complex.

Materials & Methods: The antifungal activity of the two antileishmanials was assessed by broth microdilution. The interaction between the antileishmanials and antifungal drugs (amphotericin B, itraconazole and terbinafine) was evaluated by the checkerboard assay.