Publications by authors named "Railson Pereira Souza"
Non-clinical investigations about cytotoxic and anti-platelet activities of gamma-terpinene.
Railson Pereira Souza Vinícius Duarte Pimentel Rayran Walter Ramos de Sousa Emerson Portela Sena Alda Cássia Alves da Silva
Naunyn Schmiedebergs Arch Pharmacol
October 2024
Article Synopsis
- Gamma-terpinene (γ-TPN), a monoterpene found in various plant essential oils (like tea tree and oregano), shows potential pharmacological effects on the cardiovascular system and antioxidant activities.
- The study investigated γ-TPN's cytotoxic effects and ability to reduce platelet aggregation using laboratory models, including MTT assays and platelet-rich plasma from hypertensive rats.
- Results indicated that γ-TPN has good lipid solubility, potential bioavailability, and favorable interaction with purinergic receptors, suggesting it may be promising for further research in managing thromboembolism and oxidative stress.