Publications by authors named "Rahul Sethia"

Background: Although rectal nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to be effective for the prevention of post-ERCP (endoscopic retrograde cholangiopancreatography) pancreatitis (PEP) in high-risk patients, the benefit in average-risk patients is unclear. We aimed at assessing the benefit of prophylactic rectal NSAIDs in unselected consecutive patients to prevent PEP.

Methods: All patients undergoing index ERCP procedures from January 2018 until March 2020 were included.

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Article Synopsis
  • * Out of 363 patients studied, 33 (9%) experienced hemorrhage, predominantly caused by arterial issues, with a significant portion requiring invasive treatments like radiographic angioembolization or surgery.
  • * Key risk factors for hemorrhage included persistent organ failure, large drainage catheter use, and extensive pancreatic necrosis, with hemorrhage significantly linked to increased in-hospital mortality rates (66.7% for those with hemorrhage compared to 25% for others).
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Background And Aims: Both endoscopic and laparoscopic transmural internal drainage are practiced for drainage of walled-off necrosis (WON) following acute pancreatitis (AP) but the superiority of either is not established. Our aim was to compare transperitoneal laparoscopic drainage with endoscopic drainage using either lumen apposing metal stents (LAMS) or plastic stents tailored to the amount of necrotic debris in WON.

Methods: In a randomized controlled trial, adequately powered to exclude the null hypothesis, patients with symptomatic WON were randomized to either endoscopic or laparoscopic drainage.

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Introduction: There are limited data on the effect of chronic pancreatitis (CP) on pregnancy outcomes and vice versa. Our aim was to evaluate the clinical trajectory of CP during pregnancy and its effect on pregnancy outcomes.

Methods: All female patients of child-bearing age (≥15 years) diagnosed with CP were studied from January 2004 to July 2019.

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