Discovery of Small Molecule PARKIN Activator from Antipsychotic/Anti-neuropsychiatric Drugs as Therapeutics for PD: an In Silico Repurposing Approach.

Although there is presently no cure for Parkinson's disease (PD), the available therapies are only able to lessen symptoms and preserve the quality of life. Around 10 million people globally had PD as of 2020. The widely used standard drug has recently been revealed to have several negative effects.

Evaluation of possible effects of Persea americana seeds on female reproductive hormonal and toxicity profile.

Ethnopharmacological Relevance: The seed of Avocado (Persea americana, Lauraceae), non-edible part of the fruit is used as health product. It has been reported as traditional female contraceptive and sterilizer in Peru and some Asian countries and in Nigeria as cardio-protective agent. The present study focused on the effect of hydro-methanolic seed extract of Persea americana on female hormones and toxicity profile using animal models.