Arsenic and selenium measurements in nail and hair show important relationships to Alzheimer's disease in the elderly.

Background And Research Question: The relationships of Arsenic (As) and selenium (Se) to Alzheimer's Disease (AD) are not clearly known. This case-control observational study aims to investigate the possible relationship of these elements to the diagnosis and pathophysiology of the disease.

Methods: This case-control observational study was performed using 40 AD patients in different clinical stages and 40 healthy control subjects, living in a similar environment with low As exposure.

Trace metal concentrations in hair and nails from Alzheimer's disease patients: Relations with clinical severity.

Background And Objectives: Metals, especially transition metals, seem to be important in the pathogenesis of Alzheimer disease. This study aims to determine the relationship of trace metal elements to the pathogenesis and/or course of Alzheimer Disease in terms of clinical severity.

Methods: The hair and nail trace metal levels of 62 Alzheimer Disease patients at different clinical stages (21 mild, 20 moderate, 21 severe) and 60 healthy control subjects were measured by using inductively coupled plasma-mass spectrometry.

Crystal structure of 3,4a,7,7,10a-penta-methyl-3-vinyl-dodeca-hydro-1-benzo[]chromen-9-ol isolated from .

The asymmetric unit of the title compound, CHO, contains two crystallographically independent mol-ecules (1 and 2) with similar conformations. In both mol-ecules, the cyclo-hexane rings adopt a chair conformation, while the oxane rings are also puckered. In the crystal, O-H⋯O hydrogen bonds connect adjacent mol-ecules, forming (6) helical chains located around a 2 screw axis and running along the crystallographic axis.

Erratum: Crystal structure of racemic [(1R,2S,3R,4S,6S)-2,6-bis-(furan-2-yl)-4-hy-droxy-4-(thio-phen-2-yl)cyclo-hexane-1,3-di-yl]bis-(thio-phen-2-yl-methanone). Corrigendum.

[This corrects the article DOI: 10.1107/S2056989016009452.].

Crystal structure of racemic [(1R,2S,3R,4S,6S)-2,6-bis-(furan-2-yl)-4-hy-droxy-4-(thio-phen-2-yl)cyclo-hexane-1,3-di-yl]bis-(thio-phen-2-yl-methanone).

In the title compound, C28H22O5S3, the central cyclo-hexane ring adopts a chair conformation. The atoms of the furan ring attached to the 6-position of the central cyclo-hexane ring are disordered over two sets of sites with occupancies of 0.832 (5) and 0.

Detection of free radicals in gamma-irradiated seasnail hard tissues by electron paramagnetic resonance.

Gamma-irradiated seasnail (from family of Helix lukortium) hard tissues (CaCO3) were investigated by electron paramagnetic resonance (EPR) at room temperature. The radicals produced by gamma-irradiation in seasnail were attributed to orthorhombic C*O2-, freely rotating C*O2-, orthorhombic C*O3-, axial C*O3-, and axial C*O3(3-) free radicals. Unirradiated seasnail hard tissues also feature Mn2+ ions in their EPR spectra.