Severe atypical iliac wing fracture associated with long-term bisphosphonate use.

Background: Bisphosphonate use is associated with atypical non-traumatic fractures, which are most commonly seen in the femur.

Case Presentation: We report a 63-year-old postmenopausal woman who presented acutely with progressively worsening lumbar pain radiating to her left hip for 10 days. There was no antecedent trauma.

Management of iliofemoral deep vein thrombosis with distal involvement.

Endovascular treatment of iliofemoral deep vein thrombosis (IF DVT) can become more complex when thrombus extends below the knee. This article discusses various techniques that can be used to treat IF DVT with distal involvement.

Lessons Learned With Venous Stenting: In-flow, Outflow, and Beyond.

Venous stents are being used with increasing frequency, with a multitude of dedicated venous stents now well established or emerging onto the market. This review explores the multifaceted aspects of venous stenting. We discuss the history of venous stents, indications for their use, the imaging required before, during and after stenting, as well as some technical tips and tricks which we have found to be helpful in our own daily practice with a particular focus on iliofemoral venous stenting.

Acute and chronic venous occlusion.

This review article provides an overview of acute and chronic venous occlusion, a condition that can cause significant morbidity and mortality if not diagnosed and treated promptly. The article begins with an introduction to the anatomy of the venous system, followed by a discussion of the causes and clinical features of venous occlusion. The diagnostic tools available for the assessment of venous occlusion, including imaging modalities such as ultrasound, CT, and MRI, are then discussed, along with their respective advantages and limitations.

Sharing images on social media without patient consent.

The purpose of this article is to initiate a discussion around the growing trend of sharing images of patients' scans without their consent on social media. While there are certainly merits in sharing images on social media, if undertaken without due care, it has the potential to be unprofessional and harmful to both patients and the radiology profession. In this article, I will outline some of the positive and negative aspects of sharing radiological images on social media, as well as some proposed solutions to help improve this practice.

Image-based computer modeling assessment of microwave ablation for treatment of adrenal tumors.

Purpose: To assess the feasibility of delivering microwave ablation for targeted treatment of aldosterone producing adenomas using image-based computational models.

Methods: We curated an anonymized dataset of diagnostic C-metomidate PET/CT images of 14 patients with aldosterone producing adenomas (APA). A semi-automated approach was developed to segment the APA, adrenal gland, and adjacent organs within 2 cm of the APA boundary.

Automated detection of enteric tubes misplaced in the respiratory tract on chest radiographs using deep learning with two centre validation.

Aim: To develop and test a model based on a convolutional neural network that can identify enteric tube position accurately on chest radiography.

Materials And Methods: The chest radiographs of adult patients were classified by radiologists based on enteric tube position as either critically misplaced (within the respiratory tract) or not critically misplaced (misplaced within the oesophagus or safely positioned below the diaphragm). A deep-learning model based on the 121-layer DenseNet architecture was developed using a training and validation set of 4,693 chest radiographs.

Land subsidence susceptibility mapping using PWRSTFAL framework and analytic hierarchy process: fuzzy method (case study: Damaneh-Daran Plain in the west of Isfahan Province, Iran).

Land subsidence susceptibility mapping is a necessary prerequisite for land subsidence management. Proper assessment of land subsidence requires determining parameters affecting subsidence to discover the spatial relationships with subsidence. For this purpose, two frameworks were prepared, according to the land site subsidence, eight parameters affecting the subsidence in the Damaneh-Daran plain.

The clinical significance of histone deacetylase-8 in human breast cancer.

Recent studies have shown that the histone deacetylase-8 (HDAC8), as one of the HDACs, regulates the expression and activity of various genes involved in cancer initiation and progression. The HDAC8 plays an epigenetic role to dysregulate expressions or to interact with transcription factors. Most researchers had focused on the HDAC 1-3 and 6, but today the HDAC8 isotype is a promising target in cancer therapy.

Pneumocephalus and Meningitis as Complications of Mastoiditis.

Pneumocephalus in the absence of trauma, tumour, or surgery is a rare entity. We report a case of a 73-year-old lady who presented with sepsis leading to confusion and unresponsiveness. A CT of brain revealed mastoiditis, sinusitis, and associated pneumocephalus.

PD-1/PD-L1 immune checkpoint: Potential target for cancer therapy.

Recent studies show that cancer cells are sometimes able to evade the host immunity in the tumor microenvironment. Cancer cells can express high levels of immune inhibitory signaling proteins. One of the most critical checkpoint pathways in this system is a tumor-induced immune suppression (immune checkpoint) mediated by the programmed cell death protein 1 (PD-1) and its ligand, programmed death ligand 1 (PD-L1).

Garlic () improves anxiety- and depressive-related behaviors and brain oxidative stress in diabetic rats.

This study investigated the effects of garlic on anxiety- and depression-related behaviors and brain oxidative markers in streptozotocin (STZ)-induced diabetes in rats. Fifty-six male Wistar rats were randomly divided into seven experimental groups ( = 8/group): control, diabetic + saline, diabetic + garlic, diabetic + imipramine, and diabetic + diazepam groups. Animals received garlic homogenate (0.

The Avocado Hand.

Accidental self-inflicted knife injuries to digits are a common cause of tendon and nerve injury requiring hand surgery. There has been an apparent increase in avocado related hand injuries. Classically, the patients hold the avocado in their non-dominant hand while using a knife to cut/peel the fruit with their dominant hand.

First Safety and Performance Evaluation of T45K, a Self-Assembling Peptide Barrier Hemostatic Device, After Skin Lesion Excision.

Background: The self-assembling peptide barrier T45K (SAPB-T45K) is an oligopeptide that rapidly forms a biocompatible hemostatic barrier when applied to wounds.

Objective: Evaluate safety and performance of SAPB-T45K in cutaneous surgery.

Materials And Methods: In this single-blind study, after sequential shave excision of 2 lesions, wounds were randomized (intrapatient) to SAPB-T45K or control treatment.

Traumatic Haemorrhagic Cervical Lymphadenopathy with Underlying Infectious Mononucleosis.

A 16-year-old male presented to the Emergency Department with a painful 3 × 3 cm left-sided neck swelling six hours following blunt trauma to the neck from a heavy swinging door. A CT angiogram was performed which revealed a large haemorrhagic lymph node as well as generalised cervical lymphadenopathy. The patient was eventually diagnosed with infectious mononucleosis.

1916-2016: a centenary of publications.

Last year, the centenary of the 1916 Easter rising in Ireland was marked by a commemorative programme organised by the Irish government including both historical and cultural events. The main themes of these events were remembering the past, celebrating Irish achievements and imagining our future. Reviewing the medical literature offers an insight into a century of achievement and change in Irish medicine, captured from the unique perspective of Ireland's oldest medical journal.

The diagnostic accuracy of ultrasonography for soft tissue lipomas: a systematic review.

Background: Ultrasound has been used in the diagnosis of soft-tissue lesions for well over a decade. Lipomas are the most common, benign, soft-tissue tumor and comprise adipose tissue. The sensitivity and specificity of diagnosing lipomas on ultrasound vary greatly in the literature.