Multi-compartmental risk assessment of heavy metal contamination in soil, plants, and wastewater: A model from Industrial Gazipur, Bangladesh.

Heavy metal contamination in industrial-agricultural regions poses global challenges, yet comprehensive risk assessment models addressing both ecological and human health impacts are scarce. This study introduces a novel multi-compartmental risk assessment framework applied to the Saldha River region of Gazipur, Bangladesh, a rapidly industrialising area experiencing significant environmental stress. Here, we analysed eight heavy metals (Cr, Pb, Cu, Fe, Mn, Zn, Ni, and Cd) in soil, wastewater, and plant samples (spinach, wild rice, and nut grass) via atomic absorption spectrophotometry (AAS).

Polymethylene-Interrupted, Omega-3 and Branched-Chain Fatty Acids and Stable C Values of Wild Gulf of Mexico Oysters () from the Texas Coast.

The complex fatty acid (FA) composition of the edible portion of American oysters () presents a significant analytical challenge to complete characterization. Here, we employed solvent-mediated covalent adduct chemical ionization to enable comprehensive characterization of its FA composition, with isotope ratio mass spectrometry for initial measurements of FA C signatures. Unusual polymethylene-interrupted (PMI) polyunsaturates were unequivocally identified, with 22:2(7,15) dominating at 5.

Rice grain quality alteration through manipulation of parboiling procedures to affect the concentration of macro- and micro- nutrient elements, B-vitamins, inorganic toxicants, and bacterial contamination.

A Bangladesh village rice parboiling plant was used to investigate how to improve essential elements and B-vitamin content of rice, while reducing the toxicants arsenic and cadmium, and potential bacterial pathogens. A 2 -factorial experiment was conducted where husked and de-husked rice was parboiled at different pre-parboiling soaking times, pre-parboiling soaking temperatures, parboiled through either boiling or steaming, and parboiled for 2 different times. Three rice cultivars were used.

Factors Influencing Smoking Behavior Among Japanese Employees: A Cross-Sectional Study.

Introduction: Globally, smoking causes several health risks, burdening public health and economic productivity. Evaluating employees' smoking cessation tendencies is crucial for companies and the nation. Therefore, this study examines the relationship between sociodemographic factors and three key determinants of smoking cessation: health literacy, decision balance, and self-efficacy among company employees.

Adsorption kinetics and mechanisms of nano chitosan coated cotton fiber for the removal of heavy metals from industrial effluents.

The present study successfully removed heavy metals from industrial effluent using nanochitosan-coated cotton fiber (NCCF) crosslinked with citric acid, demonstrating the potential of advanced technologies in removing heavy metals from large amounts of wastewater caused by the world's unchecked population growth and widespread industrialization that has caused pollution. Structural, morphological, and thermal properties of NCCF were determined. Results revealed that the nanochitosan component improves the adsorption capacity of cotton fiber (CF) through the increased surface area and porosity of NCCF.

Glycemic control is worse in rural compared to urban type 2 diabetes in Bangladesh, irrespective of food security status.

Background: Food insecurity (FIS) affects around 25% of Bangladesh's population, and data from developed nations report higher FIS rates among individuals with type 2 diabetes (T2D), potentially worsening glycemic control. The importance of FIS to T2D has not been studied in developing countries such as Bangladesh, with substantial disparities in healthcare access, especially between rural and urban areas. We evaluated the relationships between food insecurity and glycemic control in the context of area of residence among individuals with T2D in Bangladesh.

Tunable Multiresonant Microcavity Exciton-Polaritons in Colloidal Quantum Wells.

Optical microcavities are widely used to confine photons for exciton-polariton formation. However, their compact design often imposes limitations on spatial freedom, particularly in controlling the cavity length with the nanometer precision required for effective coupling with excitons. Existing methods for tuning resonances by integrating cavities with dynamic structures often lack sufficient resolution or a complex operation.

Groundwater quality drivers in the drought-prone Thakurgaon District, Northwestern Bangladesh: An integrated fuzzy logic and statistical modeling approach.

Groundwater quality in the drought-prone Thakurgaon District, Northwestern Bangladesh, is deteriorating due to a combination of natural and anthropogenic factors. This study evaluates the key drivers of groundwater quality degradation by employing ecotoxicological risk indices, such as the Heavy Metal Pollution Index (HPI), Heavy Metal Evaluation Index (HEI), and Nemerow's Pollution Index (NPI). An innovative fuzzy logic approach is used to integrate these indices and reduce uncertainty, while Automatic Linear Modeling (ALM) predicts the primary impacts on the Fuzzy Groundwater Quality Index (FGWQI).

Chemometric Model for Rapid Determination of Syringyl/Guaiacyl Ratio in Non-Wood by FT-NIR Spectroscopic Data.

The present study is to develop a cost-effective, non-destructive and rapid method for quantification of syringyl/guaiacyl (S/G) ratio content in non-wood lignin, which is based on FT-NIR spectroscopic data and chemometric modelling techniques. The S/G ratio in 22 non-wood lignins was determined by wet chemical method. Then the same samples were run with FT-NIR, and the spectroscopic data were pre-processed with Savitzky-Golay (S-G) on their 1st and 2nd derivatives.

A Comprehensive Review of Nanoparticle-Based Drug Delivery for Modulating PI3K/AKT/mTOR-Mediated Autophagy in Cancer.

The phosphoinositide 3-kinase (PI3K)/AKT/mammalian target of the rapamycin (mTOR) pathway plays a crucial role in the regulation of autophagy, a cellular mechanism vital for homeostasis through the degradation of damaged organelles and proteins. The dysregulation of this pathway is significantly associated with cancer progression, metastasis, and resistance to therapy. Targeting the PI3K/AKT/mTOR signaling pathway presents a promising strategy for cancer treatment; however, traditional therapeutics frequently encounter issues related to nonspecific distribution and systemic toxicity.

Maternal experience of intimate partner violence, maternal depression, and parental stress are not associated with child telomere length in Bangladesh.

Shorter telomere length (TL) is associated with an increased risk for developing chronic or age-related diseases in adults. The process of telomere shortening is accelerated in response to stress and is well characterized in adult populations from high-income countries. Prior studies suggest the relationship between stress, shorter TL, and disease risk initiates in early life.

Distinct neuronal vulnerability and metabolic dysfunctions are characteristic features of fast-progressing Alzheimer's patients with Lewy bodies.

Tau protein accumulation is linked to dementia progression in Alzheimer's disease (AD), with potential co-pathologies contributing to it. The progression of dementia in AD patients varies between individuals, and the association between co-pathology and heterogeneity in dementia progression rate remains unclear. We used longitudinal cohort data, postmortem brain tissues, and biochemical methods such as immunoassays and proteomic profiling to investigate the molecular components associated with progression rate.

Molecular and Genomic Investigation Unveils Pseudomonas putida as an Emerging Multidrug-Resistant Pathogen Linked to Bovine Clinical Mastitis.

Pseudomonas putida is one of the emerging pathogens responsible causing mastitis in lactating animals. This study investigated the prevalence, antimicrobial resistance (AMR), genetic diversity and virulence factor genes (VFGs) to highlight the pathogenic potentials of P. putida strains isolated from milk, feces and farm soil of bovine clinical mastitis (CM).

Evaluation of the relationship between consumption of carbonated soft drinks/fast food and anxiety-related sleep disturbance in school adolescents in Bangladesh.

While studies from high-income countries have shown an association between adolescents' poor dietary habits and a lack of quality sleep, there is a dearth of similar data from developing nations. This study intends to investigate the relationship between the consumption of carbonated soft drinks and fast food and sleep disturbances linked to anxiety in school-going adolescents in Bangladesh. The data used for this study came from the 2014 Bangladesh Global School-based Health Survey.

Correction: Investigating the functional and structural effect of non-synonymous single nucleotide polymorphisms in the cytotoxic T-lymphocyte antigen-4 gene: An in-silico study.

[This corrects the article DOI: 10.1371/journal.pone.

Synthesis, antibacterial activity, in silico ADMET prediction, docking, and molecular dynamics studies of substituted phenyl and furan ring containing thiazole Schiff base derivatives.

This study synthesized eighteen phenyl and furan rings containing thiazole Schiff base derivatives 2(a-r) in five series, and spectral analyses confirmed their structures. The in vitro antibacterial activities of the synthesized analogs against two gram-positive and two gram-negative bacteria were evaluated by disk diffusion technique. Compounds (2d) and (2n) produced prominently high zone of inhibition with 48.

Metformin's anticancer odyssey: Revealing multifaceted mechanisms across diverse neoplastic terrains- a critical review.

Metformin, initially prescribed as an oral hypoglycemic medication for type 2 diabetes, has recently gained attention for its potential anticancer effects. Its history dates to 1918, when guanidine, a component of the traditional European herb Galega officinalis, was found to reduce glycemia. This review precisely examines the mechanisms underlying Metformin's anticancer effects across various neoplastic conditions.

Clinical characterisation, treatment outcomes, and case fatality risk of patients with different SARS-CoV-2 variants in Bangladesh.

Background: Bangladesh underwent four waves of the coronavirus disease 2019 (COVID-19) pandemic. Analysing them is essential for understanding changes in viral behaviour, disease patterns, severity, and response to treatment. Nevertheless, data are scarce in low- and middle-income countries.

The LRP1-SHP2 pathway regulates TRPV1 sensitivity in the peripheral nervous system: Insights from amyloid beta 1-42 modulation.

Introduction: Mature adults often exhibit higher pain thresholds than younger individuals. However, this phenomenon is poorly understood, especially with regards to peripheral nervous system signaling.

Objectives: We investigated the involvement of amyloid beta (Aβ) in regulating heat pain sensitivity within the dorsal root ganglion (DRG) during adult maturation.

Survival predictors of older cancer patients in Bangladesh: A multicenter study.

Introduction: The aging of the global population has led to an increased prevalence of cancer among older adults, particularly in Asia and in low- and middle-income countries. This demographic shift presents unique challenges to healthcare delivery, especially in developing countries like Bangladesh. This study aims to analyze survival outcomes and epidemiological patterns of elderly cancer patients in Bangladesh, addressing a critical knowledge gap in geriatric oncology in low- and middle-income countries METHODS: A 27-month prospective cohort study, conducted from October 2021 to January 2024 across three hospitals in Bangladesh, included 862 cancer patients aged 60 and older, 581 of whom completed the full study period.

An assessment of the spatial and temporal distribution of nitrate and trace element concentrations in groundwater in coastal districts of Bangladesh.

Groundwater is considered a significant source of drinking water around the world. However, the naturally occurring trace elements, mostly As, B, Fe, Mn, Cu, and Zn are proven to deteriorate the groundwater quality. This study aimed to evaluate the seasonal distribution of trace metals and NO in groundwater and the associated risk to human health in the coastal region of Bangladesh.