Are we really hesitant toward routine immunization: Findings from a cross-sectional study in urban area in the tribal dominant state of India.

Background: Vaccine hesitancy has been inching up and its root cause lies in the factors that influence the vaccination. The present study was conducted to find out the proportion and factors contributing to vaccine hesitancy for routine childhood vaccinations in the slum population.

Methods: A community-based cross-sectional study was carried out among 210 children between the age group of 0 and 59 months residing in the urban slums of Ranchi in 2021.

Discrete pulp canal calcification in a case of full pulpotomy: A 2-year follow-up case report.

Pulpotomy is recognized as a promising treatment option, especially for immature permanent teeth, as it prevents the unnecessary removal of radicular pulp tissue. The aim of the study was to evaluate the clinical and radiographic outcome of full pulpotomy using Biodentine in the young permanent tooth with symptomatic irreversible pulpitis. Full pulpotomy with Biodentine was performed on a 15-year-old male patient diagnosed with irreversible pulpitis in tooth #47.

Association analysis of HSP90AA1 polymorphism with thermotolerance in tropically adapted Indian crossbred cattle.

Raising cattle is a lucrative business that operates globally but is confronted by many obstacles, such as thermal stress, which results in substantial monetary losses. A vital role of heat shock proteins (HSPs) is to protect cells from cellular damage. HSP90 is a highly prevalent, extremely adaptable gene linked to physiological resilience in thermal stress.

Organic waste recycling by vermicomposting amended with rock phosphate impacts the stability and maturity indices of vermicompost.

Recycling organic waste can help the land be nourished, properly disposed of, and protected from the negative impacts of chemical fertilizers. Organic additions like vermicompost can help restore and preserve the quality of the soil, however, producing vermicompost of a high enough standard is difficult. This study was planned to prepare vermicompost by utilizing two different organic wastes viz.

Association of udder type traits with single nucleotide polymorphisms in Sahiwal (Bos indicus) and Karan Fries ( × ) cattle.

Udder structure of milking cows is not merely vital to display the visual characteristics, but also important for high milk output and low mastitis risk incidence as well. The present study measured different udder type traits in Sahiwal () and Karan Fries () and investigated their association with single nucleotide polymorphisms in Vitamin D Receptor and Protein Tyrosine Phosphatase, Receptor Type, R genes. GG genotype of SNP rs454303072 was found to have wider rear udder, larger udder circumference, longer distance between fore-rear teats and left-right teats in Karan Fries cattle.

Udder and teat morphometry in relation to clinical mastitis in dairy cows.

The present study was undertaken to explore the association of occurrence of clinical mastitis with udder and teat morphometry in cattle. The relationship of nine udder and eight teat morphometric traits with the occurrence of clinical mastitis was analysed using a binomial logistic regression model. A significant association of the udder and teat morphometric traits with the occurrence of mastitis was observed both in Karan Fries and Sahiwal cattle.

Predictors of Breastfeeding Initiation Among Postnatal Mothers at Tertiary Care Center of a Tribal Dominant State in India: A Regression Analysis.

Background Early initiation of breastfeeding (EIBF) is one of the most important predictors for the survival of a child, spacing between two children, and prevention from childhood infections. Breastfeeding plays an important role in reducing child mortality and morbidity but the practice of EIBF globally is way behind the required time for initiation of breastfeeding after delivery. So, we planned to evaluate the early time of initiation of breastfeeding among the postnatal mothers and to determine the predictors of early initiation of breastfeeding in a tertiary hospital setting.

Genetic polymorphism in HSPB6 gene and their association with heat tolerance traits in Indian Karan Fries () cattle.

Heat shock proteins (HSPs) act as a chaperone activity ensuring the folding, unfolding, and refolding of denatured proteins, which help in a protective role during thermal stress in dairy cattle. This study aimed to detect genetic variations of the HSPB6 gene and to determine their association with heat tolerance traits in Karan Fries cattle. Five single nucleotide polymorphisms (SNPs) (SNP 1-5) were reported in the Karan Fries cattle, which included three transitions viz.

WITHDRAWN:Principal component analysis of linear udder type traits and their relationship with milk yield and composition in indigenous Sahiwal cattle.

Ahead of Print article withdrawn by publisher.

Molecular characterization and SNP identification in HSPB6 gene in Karan Fries (Bos taurus x Bos indicus) cattle.

Heat shock proteins (HSPs) act as molecular chaperones which are preferentially transcribed in response to severe perturbations of the cellular homeostasis such as heat stress. The present study was undertaken for molecular characterization and detection of genetic polymorphisms of HSPB6 gene in 100 Karan Fries Cattle. HSPB6 gene was mapped on Bos taurus autosome 18 (BTA 18), comprising three exons and two introns.

Emission estimates of particulate matter and heavy metals from mobile sources in Delhi (India).

An attempt has been made to make a comprehensive emission inventory of particulate matter (PM) of various size fractions and also of heavy metals (HMs) emitted from mobile sources (both exhaust and non-exhaust) from the road transport of Delhi, India (1991-2006). COPERT-III and 4 models were mainly used toestimate these emissions. Results show that the annual exhaust emission of PM of size upto 2.

Urban and country level greenhouse gas emissions and carbon footprints: A comparative study of a megacity, Delhi and India.

This paper describes the contribution and comparison of carbon footprints of megacity Delhi with that of India over the period from 1990 to 2000. Two published studies were taken as base to calculate carbon footprint in terms of CO2 equivalents (CO(2)-e) by taking into account CO2, CH4 and N2O emissions mainly from transport, power plants, domestic, industries, agriculture and waste sectors. It is found that carbon footprints have increased more in India (-45%) in comparison to Delhi (-33%) between 1990-2000.

Chronic exposure to arsenic causes increased cell survival, DNA damage, and increased expression of mitochondrial transcription factor A (mtTFA) in human prostate epithelial cells.

Arsenic is a known carcinogen, and its exposure is associated with cancers in multiple target organs including the prostate. Whether arsenic causes cancer by increased cell proliferation or cell survival is not clear. Additionally, mitochondria have been shown to play important roles in arsenic-induced DNA damage and carcinogenesis.

Simulated microgravity-induced epigenetic changes in human lymphocytes.

Real space flight and modeled microgravity conditions result in changes in the expression of genes that control important cellular functions. However, the mechanisms for microgravity-induced gene expression changes are not clear. The epigenetic changes of DNA methylation and chromatin histones modifications are known to regulate gene expression.

Simulated microgravity decreases DNA repair capacity and induces DNA damage in human lymphocytes.

The effect of simulated microgravity on DNA damage and apoptosis is still controversial. The objective of this study was to test whether simulated microgravity conditions affect the expression of genes for DNA repair and apoptosis. To achieve this objective, human lymphocyte cells were grown in a NASA-developed rotating wall vessel (RWV) bioreactor that simulates microgravity.

Long duration exposure to cadmium leads to increased cell survival, decreased DNA repair capacity, and genomic instability in mouse testicular Leydig cells.

Epidemiological and experimental studies have shown that cadmium is carcinogenic to human and experimental animals, however, the mechanism of cadmium-induced carcinogenesis is not clear. The aberrant expression of cell cycle and DNA repair genes resulting in increased cell proliferation and genomic instability are the characteristic features of cancer cells. The purpose of this study was to determine if exposure to cadmium can perturb cell proliferation/survival and causes genomic instability in TM3 cells, a mouse testicular Leydig cell line.